CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
NDUFS6 NDUFS6-NDUFS2 zf-CHCC(82-120) zf-CHCC(82-120) - Complex1_49kDa
NDUFS6 NDUFS6-NDUFS1 zf-CHCC(82-120) zf-CHCC(82-120) - NADH-G_4Fe-4S_3
NDUFS6 NDUFS6-NDUFS8 zf-CHCC(82-120) zf-CHCC(82-120) - Fer4_7

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA NDUFS6 NDUFS2 NDUFS6-002 ENST00000469176
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA NDUFS6 NDUFS1 NDUFS6-002 ENST00000469176
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA NDUFS6 NDUFS8 NDUFS6-002 ENST00000469176
43672213-eb65-4206-bc57-56587b08259f Lung.Lung-SCC NDUFS6 NDUFS2 NDUFS6-002 ENST00000469176
43672213-eb65-4206-bc57-56587b08259f Lung.Lung-SCC NDUFS6 NDUFS1 NDUFS6-002 ENST00000469176
43672213-eb65-4206-bc57-56587b08259f Lung.Lung-SCC NDUFS6 NDUFS8 NDUFS6-002 ENST00000469176
Interaction losses with Clinvar proteins
Gene Name
NDUFS1
NDUFS2
NDUFS6
NDUFS8