CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction lost due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain<-->Domain Interaction
NDUFS8 NDUFS8-NDUFS7 Fer4(143-166) Fer4(143-166)--Oxidored_q6
NDUFS8 NDUFS8-NDUFS2 Fer4_7(110-164) Fer4_7(110-164)--Complex1_49kDa
NDUFS8 NDUFS8-NDUFS1 Fer4_7(110-164) Fer4_7(110-164)--Molybdopterin
NDUFS8 NDUFS8-NDUFS4 Fer4_7(110-164) Fer4_7(110-164)--ETC_C1_NDUFA4
NDUFS8 NDUFS8-NDUFA12 Fer4_7(110-164) Fer4_7(110-164)--NDUFA12
NDUFS8 NDUFS8-NDUFS6 Fer4_7(110-164) Fer4_7(110-164)--zf-CHCC
NDUFS8 None None

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Protein Interaction Lost due to the MDT switch in all disease types
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Eso-AdenoCA NDUFS8 NDUFS7 NDUFS8-004 ENST00000528492
37725090-996e-4ab2-bbf6-dc3d2970e387 Eso-AdenoCA NDUFS8 NDUFS2 NDUFS8-004 ENST00000528492
37725090-996e-4ab2-bbf6-dc3d2970e387 Eso-AdenoCA NDUFS8 NDUFS1 NDUFS8-004 ENST00000528492
37725090-996e-4ab2-bbf6-dc3d2970e387 Eso-AdenoCA NDUFS8 NDUFS4 NDUFS8-004 ENST00000528492
37725090-996e-4ab2-bbf6-dc3d2970e387 Eso-AdenoCA NDUFS8 NDUFA12 NDUFS8-004 ENST00000528492
37725090-996e-4ab2-bbf6-dc3d2970e387 Eso-AdenoCA NDUFS8 NDUFS6 NDUFS8-004 ENST00000528492
50db517a-a5c7-431e-9439-cb5cffb9b954 Kidney-RCC NDUFS8 NDUFS7 NDUFS8-004 ENST00000528492
50db517a-a5c7-431e-9439-cb5cffb9b954 Kidney-RCC NDUFS8 NDUFS2 NDUFS8-004 ENST00000528492
50db517a-a5c7-431e-9439-cb5cffb9b954 Kidney-RCC NDUFS8 NDUFS1 NDUFS8-004 ENST00000528492
50db517a-a5c7-431e-9439-cb5cffb9b954 Kidney-RCC NDUFS8 NDUFS4 NDUFS8-004 ENST00000528492
50db517a-a5c7-431e-9439-cb5cffb9b954 Kidney-RCC NDUFS8 NDUFA12 NDUFS8-004 ENST00000528492
50db517a-a5c7-431e-9439-cb5cffb9b954 Kidney-RCC NDUFS8 NDUFS6 NDUFS8-004 ENST00000528492
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney-RCC NDUFS8 NDUFS7 NDUFS8-004 ENST00000528492
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney-RCC NDUFS8 NDUFS2 NDUFS8-004 ENST00000528492
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney-RCC NDUFS8 NDUFS1 NDUFS8-004 ENST00000528492
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney-RCC NDUFS8 NDUFS4 NDUFS8-004 ENST00000528492
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney-RCC NDUFS8 NDUFA12 NDUFS8-004 ENST00000528492
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney-RCC NDUFS8 NDUFS6 NDUFS8-004 ENST00000528492
b8862635-21cd-405b-b757-8ee924a7a826 Kidney-RCC NDUFS8 NDUFS7 NDUFS8-004 ENST00000528492
b8862635-21cd-405b-b757-8ee924a7a826 Kidney-RCC NDUFS8 NDUFS2 NDUFS8-004 ENST00000528492
b8862635-21cd-405b-b757-8ee924a7a826 Kidney-RCC NDUFS8 NDUFS1 NDUFS8-004 ENST00000528492
b8862635-21cd-405b-b757-8ee924a7a826 Kidney-RCC NDUFS8 NDUFS4 NDUFS8-004 ENST00000528492
b8862635-21cd-405b-b757-8ee924a7a826 Kidney-RCC NDUFS8 NDUFA12 NDUFS8-004 ENST00000528492
b8862635-21cd-405b-b757-8ee924a7a826 Kidney-RCC NDUFS8 NDUFS6 NDUFS8-004 ENST00000528492
43672213-eb65-4206-bc57-56587b08259f Lung-SCC NDUFS8 None NDUFS8-004 ENST00000528492
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin-Melanoma NDUFS8 NDUFS7 NDUFS8-004 ENST00000528492
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin-Melanoma NDUFS8 NDUFS2 NDUFS8-004 ENST00000528492
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin-Melanoma NDUFS8 NDUFS1 NDUFS8-004 ENST00000528492
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin-Melanoma NDUFS8 NDUFS4 NDUFS8-004 ENST00000528492
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin-Melanoma NDUFS8 NDUFA12 NDUFS8-004 ENST00000528492
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin-Melanoma NDUFS8 NDUFS6 NDUFS8-004 ENST00000528492
Protein Interaction Lost with Proteins annotated in Clinvar
Gene Name
NDUFA12
NDUFS1
NDUFS2
NDUFS4
NDUFS6
NDUFS7