CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
PKD1 PKD1-CDH1 Lectin_C(426-531) Lectin_C(426-531) - Cadherin
PKD1 PKD1-PKD2 PKD_channel(3712-4112) PKD_channel(3712-4112) - Ion_trans

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
e8cc9981-3f57-49cc-9779-72d1c50bc59a Kidney.Kidney-ChRCC PKD1 CDH1 PKD1-025 ENST00000568591
e8cc9981-3f57-49cc-9779-72d1c50bc59a Kidney.Kidney-ChRCC PKD1 PKD2 PKD1-025 ENST00000568591
8fbb5128-ddb8-11e4-ad8f-5ed8e2d07381 Liver.Liver-HCC PKD1 CDH1 PKD1-025 ENST00000568591
8fbb5128-ddb8-11e4-ad8f-5ed8e2d07381 Liver.Liver-HCC PKD1 PKD2 PKD1-025 ENST00000568591
8fbb9b92-ddb8-11e4-ad8f-5ed8e2d07381 Liver.Liver-HCC PKD1 CDH1 PKD1-025 ENST00000568591
8fbb9b92-ddb8-11e4-ad8f-5ed8e2d07381 Liver.Liver-HCC PKD1 PKD2 PKD1-025 ENST00000568591
Interaction losses with Clinvar proteins
Gene Name
CDH1
PKD1
PKD2