dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| POLD3 | POLD3-POLE2 | CDC27(19-466) | CDC27(19-466) - DNA_pol_E_B |
| POLD3 | POLD3-POLA2 | CDC27(19-466) | CDC27(19-466) - DNA_pol_E_B |
| POLD3 | POLD3-POLD2 | CDC27(19-466) | CDC27(19-466) - DNA_pol_E_B |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| 932c2e20-510c-4aed-879e-b69d90710b64 | Colon.ColoRect-AdenoCA | POLD3 | POLE2 | POLD3-010 | ENST00000528481 |
| 932c2e20-510c-4aed-879e-b69d90710b64 | Colon.ColoRect-AdenoCA | POLD3 | POLA2 | POLD3-010 | ENST00000528481 |
| 932c2e20-510c-4aed-879e-b69d90710b64 | Colon.ColoRect-AdenoCA | POLD3 | POLD2 | POLD3-010 | ENST00000528481 |
Interaction losses with Clinvar proteins
| Gene Name |
|---|