dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| POLR3E | POLR3E-POLR3K | Sin_N(4-434) | Sin_N(4-434) - RNA_POL_M_15KD |
| POLR3E | POLR3E-POLR3B | Sin_N(4-434) | Sin_N(4-434) - RNA_pol_Rpb2_1 |
| POLR3E | POLR3E-POLR1B | Sin_N(4-434) | Sin_N(4-434) - RNA_pol_Rpb2_1 |
| POLR3E | POLR3E-POLR3D | Sin_N(4-434) | Sin_N(4-434) - RNA_pol_Rpc4 |
| POLR3E | POLR3E-POLR3F | Sin_N(4-434) | Sin_N(4-434) - RNA_pol_Rpc34 |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| 52c2389d-71f1-4193-bea7-a8487b0dca6a | Ovary.Ovary-AdenoCA | POLR3E | POLR3K | POLR3E-003 | ENST00000418581 |
| 52c2389d-71f1-4193-bea7-a8487b0dca6a | Ovary.Ovary-AdenoCA | POLR3E | POLR3B | POLR3E-003 | ENST00000418581 |
| 52c2389d-71f1-4193-bea7-a8487b0dca6a | Ovary.Ovary-AdenoCA | POLR3E | POLR1B | POLR3E-003 | ENST00000418581 |
| 52c2389d-71f1-4193-bea7-a8487b0dca6a | Ovary.Ovary-AdenoCA | POLR3E | POLR3D | POLR3E-003 | ENST00000418581 |
| 52c2389d-71f1-4193-bea7-a8487b0dca6a | Ovary.Ovary-AdenoCA | POLR3E | POLR3F | POLR3E-003 | ENST00000418581 |