CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
POLR3E POLR3E-POLR3K Sin_N(4-434) Sin_N(4-434) - RNA_POL_M_15KD
POLR3E POLR3E-POLR3B Sin_N(4-434) Sin_N(4-434) - RNA_pol_Rpb2_1
POLR3E POLR3E-POLR1B Sin_N(4-434) Sin_N(4-434) - RNA_pol_Rpb2_1
POLR3E POLR3E-POLR3D Sin_N(4-434) Sin_N(4-434) - RNA_pol_Rpc4
POLR3E POLR3E-POLR3F Sin_N(4-434) Sin_N(4-434) - RNA_pol_Rpc34

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
0307bd0b-b59a-4996-b89d-612e72652890 Breast.Breast-AdenoCA POLR3E POLR3K POLR3E-007 ENST00000564750
0307bd0b-b59a-4996-b89d-612e72652890 Breast.Breast-AdenoCA POLR3E POLR3B POLR3E-007 ENST00000564750
0307bd0b-b59a-4996-b89d-612e72652890 Breast.Breast-AdenoCA POLR3E POLR1B POLR3E-007 ENST00000564750
0307bd0b-b59a-4996-b89d-612e72652890 Breast.Breast-AdenoCA POLR3E POLR3D POLR3E-007 ENST00000564750
0307bd0b-b59a-4996-b89d-612e72652890 Breast.Breast-AdenoCA POLR3E POLR3F POLR3E-007 ENST00000564750
09c248f8-cdd7-4c13-9085-26c56544bcf7 Breast.Breast-AdenoCA POLR3E POLR3K POLR3E-007 ENST00000564750
09c248f8-cdd7-4c13-9085-26c56544bcf7 Breast.Breast-AdenoCA POLR3E POLR3B POLR3E-007 ENST00000564750
09c248f8-cdd7-4c13-9085-26c56544bcf7 Breast.Breast-AdenoCA POLR3E POLR1B POLR3E-007 ENST00000564750
09c248f8-cdd7-4c13-9085-26c56544bcf7 Breast.Breast-AdenoCA POLR3E POLR3D POLR3E-007 ENST00000564750
09c248f8-cdd7-4c13-9085-26c56544bcf7 Breast.Breast-AdenoCA POLR3E POLR3F POLR3E-007 ENST00000564750
0c9fe532-3920-4a59-b348-65b184c0eff4 Breast.Breast-AdenoCA POLR3E POLR3K POLR3E-007 ENST00000564750
0c9fe532-3920-4a59-b348-65b184c0eff4 Breast.Breast-AdenoCA POLR3E POLR3B POLR3E-007 ENST00000564750
0c9fe532-3920-4a59-b348-65b184c0eff4 Breast.Breast-AdenoCA POLR3E POLR1B POLR3E-007 ENST00000564750
0c9fe532-3920-4a59-b348-65b184c0eff4 Breast.Breast-AdenoCA POLR3E POLR3D POLR3E-007 ENST00000564750
0c9fe532-3920-4a59-b348-65b184c0eff4 Breast.Breast-AdenoCA POLR3E POLR3F POLR3E-007 ENST00000564750
1ccf908a-7620-4af8-b83f-0e287f3655c5 Breast.Breast-AdenoCA POLR3E POLR3K POLR3E-007 ENST00000564750
1ccf908a-7620-4af8-b83f-0e287f3655c5 Breast.Breast-AdenoCA POLR3E POLR3B POLR3E-007 ENST00000564750
1ccf908a-7620-4af8-b83f-0e287f3655c5 Breast.Breast-AdenoCA POLR3E POLR1B POLR3E-007 ENST00000564750
1ccf908a-7620-4af8-b83f-0e287f3655c5 Breast.Breast-AdenoCA POLR3E POLR3D POLR3E-007 ENST00000564750
1ccf908a-7620-4af8-b83f-0e287f3655c5 Breast.Breast-AdenoCA POLR3E POLR3F POLR3E-007 ENST00000564750
6d2744ba-4817-482b-ad46-2e4e0897ad88 Breast.Breast-AdenoCA POLR3E POLR3K POLR3E-007 ENST00000564750
6d2744ba-4817-482b-ad46-2e4e0897ad88 Breast.Breast-AdenoCA POLR3E POLR3B POLR3E-007 ENST00000564750
6d2744ba-4817-482b-ad46-2e4e0897ad88 Breast.Breast-AdenoCA POLR3E POLR1B POLR3E-007 ENST00000564750
6d2744ba-4817-482b-ad46-2e4e0897ad88 Breast.Breast-AdenoCA POLR3E POLR3D POLR3E-007 ENST00000564750
6d2744ba-4817-482b-ad46-2e4e0897ad88 Breast.Breast-AdenoCA POLR3E POLR3F POLR3E-007 ENST00000564750
98b2b18a-004d-459c-8aba-499d06897910 Breast.Breast-AdenoCA POLR3E POLR3K POLR3E-007 ENST00000564750
98b2b18a-004d-459c-8aba-499d06897910 Breast.Breast-AdenoCA POLR3E POLR3B POLR3E-007 ENST00000564750
98b2b18a-004d-459c-8aba-499d06897910 Breast.Breast-AdenoCA POLR3E POLR1B POLR3E-007 ENST00000564750
98b2b18a-004d-459c-8aba-499d06897910 Breast.Breast-AdenoCA POLR3E POLR3D POLR3E-007 ENST00000564750
98b2b18a-004d-459c-8aba-499d06897910 Breast.Breast-AdenoCA POLR3E POLR3F POLR3E-007 ENST00000564750
c09e8a88-5a82-4fd6-8d03-ef3ecb988003 Breast.Breast-AdenoCA POLR3E POLR3K POLR3E-007 ENST00000564750
c09e8a88-5a82-4fd6-8d03-ef3ecb988003 Breast.Breast-AdenoCA POLR3E POLR3B POLR3E-007 ENST00000564750
c09e8a88-5a82-4fd6-8d03-ef3ecb988003 Breast.Breast-AdenoCA POLR3E POLR1B POLR3E-007 ENST00000564750
c09e8a88-5a82-4fd6-8d03-ef3ecb988003 Breast.Breast-AdenoCA POLR3E POLR3D POLR3E-007 ENST00000564750
c09e8a88-5a82-4fd6-8d03-ef3ecb988003 Breast.Breast-AdenoCA POLR3E POLR3F POLR3E-007 ENST00000564750
fac9101c-a974-4415-9eac-d2d433d02b13 Breast.Breast-AdenoCA POLR3E POLR3K POLR3E-007 ENST00000564750
fac9101c-a974-4415-9eac-d2d433d02b13 Breast.Breast-AdenoCA POLR3E POLR3B POLR3E-007 ENST00000564750
fac9101c-a974-4415-9eac-d2d433d02b13 Breast.Breast-AdenoCA POLR3E POLR1B POLR3E-007 ENST00000564750
fac9101c-a974-4415-9eac-d2d433d02b13 Breast.Breast-AdenoCA POLR3E POLR3D POLR3E-007 ENST00000564750
fac9101c-a974-4415-9eac-d2d433d02b13 Breast.Breast-AdenoCA POLR3E POLR3F POLR3E-007 ENST00000564750
93543d44-72a0-4f35-bc35-3acffc85ced6 Kidney.Kidney-ChRCC POLR3E POLR3K POLR3E-007 ENST00000564750
93543d44-72a0-4f35-bc35-3acffc85ced6 Kidney.Kidney-ChRCC POLR3E POLR3B POLR3E-007 ENST00000564750
93543d44-72a0-4f35-bc35-3acffc85ced6 Kidney.Kidney-ChRCC POLR3E POLR1B POLR3E-007 ENST00000564750
93543d44-72a0-4f35-bc35-3acffc85ced6 Kidney.Kidney-ChRCC POLR3E POLR3D POLR3E-007 ENST00000564750
93543d44-72a0-4f35-bc35-3acffc85ced6 Kidney.Kidney-ChRCC POLR3E POLR3F POLR3E-007 ENST00000564750
d42c9589-3960-4964-be28-83d275bdc672 Kidney.Kidney-ChRCC POLR3E POLR3K POLR3E-007 ENST00000564750
d42c9589-3960-4964-be28-83d275bdc672 Kidney.Kidney-ChRCC POLR3E POLR3B POLR3E-007 ENST00000564750
d42c9589-3960-4964-be28-83d275bdc672 Kidney.Kidney-ChRCC POLR3E POLR1B POLR3E-007 ENST00000564750
d42c9589-3960-4964-be28-83d275bdc672 Kidney.Kidney-ChRCC POLR3E POLR3D POLR3E-007 ENST00000564750
d42c9589-3960-4964-be28-83d275bdc672 Kidney.Kidney-ChRCC POLR3E POLR3F POLR3E-007 ENST00000564750
26490a5f-6d48-4864-a1ab-7caa14924c73 Thyroid.Thy-AdenoCA POLR3E POLR3K POLR3E-007 ENST00000564750
26490a5f-6d48-4864-a1ab-7caa14924c73 Thyroid.Thy-AdenoCA POLR3E POLR3B POLR3E-007 ENST00000564750
26490a5f-6d48-4864-a1ab-7caa14924c73 Thyroid.Thy-AdenoCA POLR3E POLR1B POLR3E-007 ENST00000564750
26490a5f-6d48-4864-a1ab-7caa14924c73 Thyroid.Thy-AdenoCA POLR3E POLR3D POLR3E-007 ENST00000564750
26490a5f-6d48-4864-a1ab-7caa14924c73 Thyroid.Thy-AdenoCA POLR3E POLR3F POLR3E-007 ENST00000564750
Interaction losses with Clinvar proteins
Gene Name
POLR1B
POLR3B
POLR3F
POLR3K