CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction lost due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain<-->Domain Interaction
PSEN1 PSEN1-APH1B Presenilin(71-458) Presenilin(71-458)--Aph-1
PSEN1 PSEN1-APH1A Presenilin(71-458) Presenilin(71-458)--Aph-1
PSEN1 PSEN1-PSENEN Presenilin(71-458) Presenilin(71-458)--PEN-2
PSEN1 PSEN1-AC002398.9 Presenilin(71-458) Presenilin(71-458)--PEN-2

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Protein Interaction Lost due to the MDT switch in all disease types
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
008292c8-81f5-4930-b179-a198686fc79b Kidney-RCC PSEN1 APH1B PSEN1-201 ENST00000261970
008292c8-81f5-4930-b179-a198686fc79b Kidney-RCC PSEN1 APH1A PSEN1-201 ENST00000261970
008292c8-81f5-4930-b179-a198686fc79b Kidney-RCC PSEN1 PSENEN PSEN1-201 ENST00000261970
008292c8-81f5-4930-b179-a198686fc79b Kidney-RCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
1d43f7a5-43ac-4861-b4a7-7bfce13ac2c5 Kidney-RCC PSEN1 APH1B PSEN1-201 ENST00000261970
1d43f7a5-43ac-4861-b4a7-7bfce13ac2c5 Kidney-RCC PSEN1 APH1A PSEN1-201 ENST00000261970
1d43f7a5-43ac-4861-b4a7-7bfce13ac2c5 Kidney-RCC PSEN1 PSENEN PSEN1-201 ENST00000261970
1d43f7a5-43ac-4861-b4a7-7bfce13ac2c5 Kidney-RCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
22f1d19e-14f8-403e-9e48-663da7508bf2 Kidney-RCC PSEN1 APH1B PSEN1-201 ENST00000261970
22f1d19e-14f8-403e-9e48-663da7508bf2 Kidney-RCC PSEN1 APH1A PSEN1-201 ENST00000261970
22f1d19e-14f8-403e-9e48-663da7508bf2 Kidney-RCC PSEN1 PSENEN PSEN1-201 ENST00000261970
22f1d19e-14f8-403e-9e48-663da7508bf2 Kidney-RCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
278030c0-cf38-4aee-bdb2-b918f009a658 Kidney-RCC PSEN1 APH1B PSEN1-201 ENST00000261970
278030c0-cf38-4aee-bdb2-b918f009a658 Kidney-RCC PSEN1 APH1A PSEN1-201 ENST00000261970
278030c0-cf38-4aee-bdb2-b918f009a658 Kidney-RCC PSEN1 PSENEN PSEN1-201 ENST00000261970
278030c0-cf38-4aee-bdb2-b918f009a658 Kidney-RCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
2fecf6cb-e69b-43f5-b5b4-3f2d32a7ff44 Kidney-RCC PSEN1 APH1B PSEN1-201 ENST00000261970
2fecf6cb-e69b-43f5-b5b4-3f2d32a7ff44 Kidney-RCC PSEN1 APH1A PSEN1-201 ENST00000261970
2fecf6cb-e69b-43f5-b5b4-3f2d32a7ff44 Kidney-RCC PSEN1 PSENEN PSEN1-201 ENST00000261970
2fecf6cb-e69b-43f5-b5b4-3f2d32a7ff44 Kidney-RCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
4eabf441-dfaa-4c36-a0a4-8897d4008f3f Kidney-RCC PSEN1 APH1B PSEN1-201 ENST00000261970
4eabf441-dfaa-4c36-a0a4-8897d4008f3f Kidney-RCC PSEN1 APH1A PSEN1-201 ENST00000261970
4eabf441-dfaa-4c36-a0a4-8897d4008f3f Kidney-RCC PSEN1 PSENEN PSEN1-201 ENST00000261970
4eabf441-dfaa-4c36-a0a4-8897d4008f3f Kidney-RCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
536d11ba-aa02-4443-96e8-6e9e9898ceb7 Kidney-RCC PSEN1 APH1B PSEN1-201 ENST00000261970
536d11ba-aa02-4443-96e8-6e9e9898ceb7 Kidney-RCC PSEN1 APH1A PSEN1-201 ENST00000261970
536d11ba-aa02-4443-96e8-6e9e9898ceb7 Kidney-RCC PSEN1 PSENEN PSEN1-201 ENST00000261970
536d11ba-aa02-4443-96e8-6e9e9898ceb7 Kidney-RCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney-RCC PSEN1 APH1B PSEN1-201 ENST00000261970
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney-RCC PSEN1 APH1A PSEN1-201 ENST00000261970
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney-RCC PSEN1 PSENEN PSEN1-201 ENST00000261970
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney-RCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
b8862635-21cd-405b-b757-8ee924a7a826 Kidney-RCC PSEN1 APH1B PSEN1-201 ENST00000261970
b8862635-21cd-405b-b757-8ee924a7a826 Kidney-RCC PSEN1 APH1A PSEN1-201 ENST00000261970
b8862635-21cd-405b-b757-8ee924a7a826 Kidney-RCC PSEN1 PSENEN PSEN1-201 ENST00000261970
b8862635-21cd-405b-b757-8ee924a7a826 Kidney-RCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
8fbcbc02-ddb8-11e4-ad8f-5ed8e2d07381 Biliary-AdenoCA PSEN1 APH1B PSEN1-201 ENST00000261970
8fbcbc02-ddb8-11e4-ad8f-5ed8e2d07381 Biliary-AdenoCA PSEN1 APH1A PSEN1-201 ENST00000261970
8fbcbc02-ddb8-11e4-ad8f-5ed8e2d07381 Biliary-AdenoCA PSEN1 PSENEN PSEN1-201 ENST00000261970
8fbcbc02-ddb8-11e4-ad8f-5ed8e2d07381 Biliary-AdenoCA PSEN1 AC002398.9 PSEN1-201 ENST00000261970
56e6f602-0afb-434e-b28e-665d923ad781 Liver-HCC PSEN1 APH1B PSEN1-201 ENST00000261970
56e6f602-0afb-434e-b28e-665d923ad781 Liver-HCC PSEN1 APH1A PSEN1-201 ENST00000261970
56e6f602-0afb-434e-b28e-665d923ad781 Liver-HCC PSEN1 PSENEN PSEN1-201 ENST00000261970
56e6f602-0afb-434e-b28e-665d923ad781 Liver-HCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
5bd6ca42-16ca-484f-877f-cda4fb3f93a8 Liver-HCC PSEN1 APH1B PSEN1-201 ENST00000261970
5bd6ca42-16ca-484f-877f-cda4fb3f93a8 Liver-HCC PSEN1 APH1A PSEN1-201 ENST00000261970
5bd6ca42-16ca-484f-877f-cda4fb3f93a8 Liver-HCC PSEN1 PSENEN PSEN1-201 ENST00000261970
5bd6ca42-16ca-484f-877f-cda4fb3f93a8 Liver-HCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
6a2cafbb-2824-4727-b950-0c2bdcf26358 Liver-HCC PSEN1 APH1B PSEN1-201 ENST00000261970
6a2cafbb-2824-4727-b950-0c2bdcf26358 Liver-HCC PSEN1 APH1A PSEN1-201 ENST00000261970
6a2cafbb-2824-4727-b950-0c2bdcf26358 Liver-HCC PSEN1 PSENEN PSEN1-201 ENST00000261970
6a2cafbb-2824-4727-b950-0c2bdcf26358 Liver-HCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
8fb8c084-ddb8-11e4-ad8f-5ed8e2d07381 Liver-HCC PSEN1 APH1B PSEN1-201 ENST00000261970
8fb8c084-ddb8-11e4-ad8f-5ed8e2d07381 Liver-HCC PSEN1 APH1A PSEN1-201 ENST00000261970
8fb8c084-ddb8-11e4-ad8f-5ed8e2d07381 Liver-HCC PSEN1 PSENEN PSEN1-201 ENST00000261970
8fb8c084-ddb8-11e4-ad8f-5ed8e2d07381 Liver-HCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
e642839c-9891-4ff0-93c4-556d81572af9 Liver-HCC PSEN1 APH1B PSEN1-201 ENST00000261970
e642839c-9891-4ff0-93c4-556d81572af9 Liver-HCC PSEN1 APH1A PSEN1-201 ENST00000261970
e642839c-9891-4ff0-93c4-556d81572af9 Liver-HCC PSEN1 PSENEN PSEN1-201 ENST00000261970
e642839c-9891-4ff0-93c4-556d81572af9 Liver-HCC PSEN1 AC002398.9 PSEN1-201 ENST00000261970
Protein Interaction Lost with Proteins annotated in Clinvar
Gene Name
PSENEN