CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction lost due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain<-->Domain Interaction
RASGRP2 RASGRP2-RAF1 C1_1(499-550) C1_1(499-550)--Pkinase
RASGRP2 RASGRP2-RASGRP1 C1_1(499-550) C1_1(499-550)--C1_1
RASGRP2 RASGRP2-APBB1IP C1_1(499-550) C1_1(499-550)--PH
RASGRP2 RASGRP2-RRAS RasGEF(153-324) RasGEF(153-324)--Ras
RASGRP2 RASGRP2-RAP1B RasGEF(153-324) RasGEF(153-324)--Ras
RASGRP2 RASGRP2-MRAS RasGEF(153-324) RasGEF(153-324)--Ras
RASGRP2 RASGRP2-HRAS RasGEF(153-324) RasGEF(153-324)--Ras
RASGRP2 RASGRP2-RAP1A RasGEF(153-324) RasGEF(153-324)--Ras
RASGRP2 RASGRP2-NRAS RasGEF(153-324) RasGEF(153-324)--Ras

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Protein Interaction Lost with Proteins annotated in Clinvar
Gene Name
HRAS
MRAS
NRAS
RAF1
RASGRP1