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Specific dMDT
Disease-type-specific MDTs
Lost Domain in dMDT
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Gene Name:
Transcript ID:
Transcript Name:
dMDT Interaction Network
Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name
Interaction Lost
Lost Domain (Region)
Lost Domain - Domain Interaction
RAVER1
RAVER1
-VCL
RRM_1
(152-220)
RRM_1
(152-220) -
Vinculin
RAVER1
RAVER1
-SF3B1
RRM_1
(152-220)
RRM_1
(152-220) -
SF3b1
Network Density Score:
%
The local network of this protein has more interaction than
% of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
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Sample ID
Disease Type
Gene Name 1
Gene Name 2
Transcript Name
dMDT
310820cc-fc05-45c6-8f04-a44db0828686
Colon.ColoRect-AdenoCA
RAVER1
VCL
RAVER1-004
ENST00000591969
310820cc-fc05-45c6-8f04-a44db0828686
Colon.ColoRect-AdenoCA
RAVER1
SF3B1
RAVER1-004
ENST00000591969
82bb01e9-a659-417b-b9e8-831a76277a21
Colon.ColoRect-AdenoCA
RAVER1
VCL
RAVER1-004
ENST00000591969
82bb01e9-a659-417b-b9e8-831a76277a21
Colon.ColoRect-AdenoCA
RAVER1
SF3B1
RAVER1-004
ENST00000591969
37725090-996e-4ab2-bbf6-dc3d2970e387
Esophagus.Eso-AdenoCA
RAVER1
VCL
RAVER1-004
ENST00000591969
37725090-996e-4ab2-bbf6-dc3d2970e387
Esophagus.Eso-AdenoCA
RAVER1
SF3B1
RAVER1-004
ENST00000591969
Interaction losses with Clinvar proteins
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Gene Name
SF3B1
VCL