CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
RBCK1 RBCK1-UBC IBR(440-476) IBR(440-476) - ubiquitin
RBCK1 RBCK1-RNF31 IBR(440-476) IBR(440-476) - IBR
RBCK1 RBCK1-UBE2D3 zf-RING_2(281-324) zf-RING_2(281-324) - UQ_con

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
381b51af-d1f7-41db-a69e-49d681b3ef39 Bladder.Bladder-TCC RBCK1 UBC RBCK1-001 ENST00000475269
381b51af-d1f7-41db-a69e-49d681b3ef39 Bladder.Bladder-TCC RBCK1 RNF31 RBCK1-001 ENST00000475269
381b51af-d1f7-41db-a69e-49d681b3ef39 Bladder.Bladder-TCC RBCK1 UBE2D3 RBCK1-001 ENST00000475269
3c499f07-67e2-4032-a0b5-b9edd90035f7 Bladder.Bladder-TCC RBCK1 UBC RBCK1-001 ENST00000475269
3c499f07-67e2-4032-a0b5-b9edd90035f7 Bladder.Bladder-TCC RBCK1 RNF31 RBCK1-001 ENST00000475269
3c499f07-67e2-4032-a0b5-b9edd90035f7 Bladder.Bladder-TCC RBCK1 UBE2D3 RBCK1-001 ENST00000475269
5968C8D3-5F1A-4EB8-8D9B-8BD3FD3FD9F1 Bladder.Bladder-TCC RBCK1 UBC RBCK1-001 ENST00000475269
5968C8D3-5F1A-4EB8-8D9B-8BD3FD3FD9F1 Bladder.Bladder-TCC RBCK1 RNF31 RBCK1-001 ENST00000475269
5968C8D3-5F1A-4EB8-8D9B-8BD3FD3FD9F1 Bladder.Bladder-TCC RBCK1 UBE2D3 RBCK1-001 ENST00000475269
B290727B-23ED-4E73-9071-CF2C06671430 Bladder.Bladder-TCC RBCK1 UBC RBCK1-001 ENST00000475269
B290727B-23ED-4E73-9071-CF2C06671430 Bladder.Bladder-TCC RBCK1 RNF31 RBCK1-001 ENST00000475269
B290727B-23ED-4E73-9071-CF2C06671430 Bladder.Bladder-TCC RBCK1 UBE2D3 RBCK1-001 ENST00000475269
01370d42-f75c-4532-9b9c-24ff7302b033 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
01370d42-f75c-4532-9b9c-24ff7302b033 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
01370d42-f75c-4532-9b9c-24ff7302b033 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
08c54c9c-195c-4754-83af-a97544d0eb12 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
08c54c9c-195c-4754-83af-a97544d0eb12 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
08c54c9c-195c-4754-83af-a97544d0eb12 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
1fe98b05-6803-4803-83cd-a59e794b956e Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
1fe98b05-6803-4803-83cd-a59e794b956e Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
1fe98b05-6803-4803-83cd-a59e794b956e Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
34980e1d-956b-4d89-8bf2-dcc008dbaad7 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
34980e1d-956b-4d89-8bf2-dcc008dbaad7 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
34980e1d-956b-4d89-8bf2-dcc008dbaad7 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
3fc1c7a8-e5ad-4a4e-89ab-ddf12aa11a3b Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
3fc1c7a8-e5ad-4a4e-89ab-ddf12aa11a3b Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
3fc1c7a8-e5ad-4a4e-89ab-ddf12aa11a3b Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
433b49ba-949b-4914-985a-be19b3b32502 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
433b49ba-949b-4914-985a-be19b3b32502 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
433b49ba-949b-4914-985a-be19b3b32502 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
60534f8f-970a-4308-9844-a3a41dd6c187 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
60534f8f-970a-4308-9844-a3a41dd6c187 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
60534f8f-970a-4308-9844-a3a41dd6c187 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
785856FC-D042-4B7F-A137-95B17C59B876 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
785856FC-D042-4B7F-A137-95B17C59B876 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
785856FC-D042-4B7F-A137-95B17C59B876 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
7b53ba9f-506e-4af7-9752-ae50e4445880 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
7b53ba9f-506e-4af7-9752-ae50e4445880 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
7b53ba9f-506e-4af7-9752-ae50e4445880 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
98b2b18a-004d-459c-8aba-499d06897910 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
98b2b18a-004d-459c-8aba-499d06897910 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
98b2b18a-004d-459c-8aba-499d06897910 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
a4cb04f5-91b3-40ba-8005-b1df46d6b555 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
a4cb04f5-91b3-40ba-8005-b1df46d6b555 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
a4cb04f5-91b3-40ba-8005-b1df46d6b555 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
a6b72c40-c921-4159-abad-b64e20619241 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
a6b72c40-c921-4159-abad-b64e20619241 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
a6b72c40-c921-4159-abad-b64e20619241 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
d6301614-9ba7-4632-bdca-ac1b11e8e811 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
d6301614-9ba7-4632-bdca-ac1b11e8e811 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
d6301614-9ba7-4632-bdca-ac1b11e8e811 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
edda9023-a8d9-45dc-af21-5bba663967e4 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
edda9023-a8d9-45dc-af21-5bba663967e4 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
edda9023-a8d9-45dc-af21-5bba663967e4 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
f6e76192-c4ed-485f-bb51-1b752bd7f544 Breast.Breast-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
f6e76192-c4ed-485f-bb51-1b752bd7f544 Breast.Breast-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
f6e76192-c4ed-485f-bb51-1b752bd7f544 Breast.Breast-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
1a6ee24e-975c-4ba8-8cc3-666555fb89d6 CervixUteri.Cervix-SCC RBCK1 UBC RBCK1-001 ENST00000475269
1a6ee24e-975c-4ba8-8cc3-666555fb89d6 CervixUteri.Cervix-SCC RBCK1 RNF31 RBCK1-001 ENST00000475269
1a6ee24e-975c-4ba8-8cc3-666555fb89d6 CervixUteri.Cervix-SCC RBCK1 UBE2D3 RBCK1-001 ENST00000475269
1e7b2ed2-be35-4cce-a613-9c8203c49ebb CervixUteri.Cervix-SCC RBCK1 UBC RBCK1-001 ENST00000475269
1e7b2ed2-be35-4cce-a613-9c8203c49ebb CervixUteri.Cervix-SCC RBCK1 RNF31 RBCK1-001 ENST00000475269
1e7b2ed2-be35-4cce-a613-9c8203c49ebb CervixUteri.Cervix-SCC RBCK1 UBE2D3 RBCK1-001 ENST00000475269
3f679347-cd3b-4711-aa6c-e5d87fa93052 CervixUteri.Cervix-SCC RBCK1 UBC RBCK1-001 ENST00000475269
3f679347-cd3b-4711-aa6c-e5d87fa93052 CervixUteri.Cervix-SCC RBCK1 RNF31 RBCK1-001 ENST00000475269
3f679347-cd3b-4711-aa6c-e5d87fa93052 CervixUteri.Cervix-SCC RBCK1 UBE2D3 RBCK1-001 ENST00000475269
a4de3863-03d5-44b0-b711-87aadcb29008 CervixUteri.Cervix-SCC RBCK1 UBC RBCK1-001 ENST00000475269
a4de3863-03d5-44b0-b711-87aadcb29008 CervixUteri.Cervix-SCC RBCK1 RNF31 RBCK1-001 ENST00000475269
a4de3863-03d5-44b0-b711-87aadcb29008 CervixUteri.Cervix-SCC RBCK1 UBE2D3 RBCK1-001 ENST00000475269
a6a4630e-3d28-4a38-8c9f-29fc0c7b380a CervixUteri.Cervix-SCC RBCK1 UBC RBCK1-001 ENST00000475269
a6a4630e-3d28-4a38-8c9f-29fc0c7b380a CervixUteri.Cervix-SCC RBCK1 RNF31 RBCK1-001 ENST00000475269
a6a4630e-3d28-4a38-8c9f-29fc0c7b380a CervixUteri.Cervix-SCC RBCK1 UBE2D3 RBCK1-001 ENST00000475269
0c0660d1-2d98-442a-95f0-593fbceafae8 Ovary.Ovary-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
0c0660d1-2d98-442a-95f0-593fbceafae8 Ovary.Ovary-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
0c0660d1-2d98-442a-95f0-593fbceafae8 Ovary.Ovary-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
52c2389d-71f1-4193-bea7-a8487b0dca6a Ovary.Ovary-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
52c2389d-71f1-4193-bea7-a8487b0dca6a Ovary.Ovary-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
52c2389d-71f1-4193-bea7-a8487b0dca6a Ovary.Ovary-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
97ae23fe-4252-402e-808b-f8d52691e0a5 Ovary.Ovary-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
97ae23fe-4252-402e-808b-f8d52691e0a5 Ovary.Ovary-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
97ae23fe-4252-402e-808b-f8d52691e0a5 Ovary.Ovary-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
c02d7082-de9b-4d72-b457-f1da55aadad8 Ovary.Ovary-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
c02d7082-de9b-4d72-b457-f1da55aadad8 Ovary.Ovary-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
c02d7082-de9b-4d72-b457-f1da55aadad8 Ovary.Ovary-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
c58dcf0f-d29b-4fdc-910a-b5b8101a25fb Ovary.Ovary-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
c58dcf0f-d29b-4fdc-910a-b5b8101a25fb Ovary.Ovary-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
c58dcf0f-d29b-4fdc-910a-b5b8101a25fb Ovary.Ovary-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
0e842eda-bb7f-4f4a-b1bc-9d6dcf563125 CervixUteri.Cervix-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
0e842eda-bb7f-4f4a-b1bc-9d6dcf563125 CervixUteri.Cervix-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
0e842eda-bb7f-4f4a-b1bc-9d6dcf563125 CervixUteri.Cervix-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
721c59a5-22b6-4388-a47d-d0108ea2c1aa CervixUteri.Cervix-AdenoCA RBCK1 UBC RBCK1-001 ENST00000475269
721c59a5-22b6-4388-a47d-d0108ea2c1aa CervixUteri.Cervix-AdenoCA RBCK1 RNF31 RBCK1-001 ENST00000475269
721c59a5-22b6-4388-a47d-d0108ea2c1aa CervixUteri.Cervix-AdenoCA RBCK1 UBE2D3 RBCK1-001 ENST00000475269
Interaction losses with Clinvar proteins
Gene Name
RBCK1