CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
RIT1 RIT1-BRAF Ras(23-183) Ras(23-183) - Pkinase
RIT1 RIT1-RIT2 Ras(23-183) Ras(23-183) - Ras

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL RIT1 BRAF RIT1-005 ENST00000539040
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL RIT1 RIT2 RIT1-005 ENST00000539040
Interaction losses with Clinvar proteins
Gene Name
BRAF
RIT1