dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| SAE1 | SAE1-UBE2I | ThiF(35-168) | ThiF(35-168) - UQ_con |
| SAE1 | SAE1-UBC | ThiF(35-168) | ThiF(35-168) - ubiquitin |
| SAE1 | SAE1-UBA2 | ThiF(35-168) | ThiF(35-168) - ThiF |
| SAE1 | SAE1-SUMO4 | ThiF(35-168) | ThiF(35-168) - Rad60-SLD |
| SAE1 | SAE1-SUMO3 | ThiF(35-168) | ThiF(35-168) - Rad60-SLD |
| SAE1 | SAE1-SUMO1 | ThiF(35-168) | ThiF(35-168) - Rad60-SLD |
| SAE1 | SAE1-SUMO2 | ThiF(35-168) | ThiF(35-168) - Rad60-SLD |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| SRR19243441 | Alzheimer's disease | SAE1 | UBE2I | SAE1-007 | ENST00000596995 |
| SRR19243441 | Alzheimer's disease | SAE1 | UBC | SAE1-007 | ENST00000596995 |
| SRR19243441 | Alzheimer's disease | SAE1 | UBA2 | SAE1-007 | ENST00000596995 |
| SRR19243441 | Alzheimer's disease | SAE1 | SUMO4 | SAE1-007 | ENST00000596995 |
| SRR19243441 | Alzheimer's disease | SAE1 | SUMO3 | SAE1-007 | ENST00000596995 |
| SRR19243441 | Alzheimer's disease | SAE1 | SUMO1 | SAE1-007 | ENST00000596995 |
| SRR19243441 | Alzheimer's disease | SAE1 | SUMO2 | SAE1-007 | ENST00000596995 |