CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
SGK1 SGK1-INSR Pkinase(193-448) Pkinase(193-448) - fn3
SGK1 SGK1-RAF1 Pkinase(193-448) Pkinase(193-448) - Pkinase
SGK1 SGK1-SGK2 Pkinase(193-448) Pkinase(193-448) - Pkinase
SGK1 SGK1-PDPK1 Pkinase(193-448) Pkinase(193-448) - Pkinase
SGK1 SGK1-GRB14 Pkinase(193-448) Pkinase(193-448) - PH
SGK1 SGK1-HSP90AA1 Pkinase(193-448) Pkinase(193-448) - HSP90
SGK1 SGK1-RPS27A Pkinase(193-448) Pkinase(193-448) - ubiquitin
SGK1 SGK1-UBB Pkinase(193-448) Pkinase(193-448) - ubiquitin
SGK1 SGK1-UBC Pkinase(193-448) Pkinase(193-448) - ubiquitin
SGK1 SGK1-UBA52 Pkinase(193-448) Pkinase(193-448) - ubiquitin
SGK1 SGK1-CDKN1B Pkinase(193-448) Pkinase(193-448) - CDI
SGK1 SGK1-SRC Pkinase(193-448) Pkinase(193-448) - Pkinase_Tyr
SGK1 SGK1-NOTCH1 Pkinase(193-448) Pkinase(193-448) - Ank_2

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Interaction losses with Clinvar proteins
Gene Name
CDKN1B
INSR
NOTCH1
RAF1
SRC