CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
SIRT1 SIRT1-SIRT2 SIR2(261-447) SIR2(261-447) - SIR2

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
22e154de-0e3b-443b-8420-48d68d6c1ce4 Bladder.Bladder-TCC SIRT1 SIRT2 SIRT1-002 ENST00000406900
94447759-c20c-49f5-b51f-cbfdea41f2e8 Bladder.Bladder-TCC SIRT1 SIRT2 SIRT1-002 ENST00000406900
b5036d12-d9cc-46a4-b60a-49740310380c Bladder.Bladder-TCC SIRT1 SIRT2 SIRT1-002 ENST00000406900
febead73-3b12-44e6-8bab-a7cfa7bf1129 Bladder.Bladder-TCC SIRT1 SIRT2 SIRT1-002 ENST00000406900
Interaction losses with Clinvar proteins
Gene Name