CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
SMG5 SMG5-SMG6 EST1_DNA_bind(647-744) EST1_DNA_bind(647-744) - EST1_DNA_bind
SMG5 SMG5-SMG7 EST1_DNA_bind(647-744) EST1_DNA_bind(647-744) - EST1_DNA_bind

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA SMG5 SMG6 SMG5-201 ENST00000368267
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA SMG5 SMG7 SMG5-201 ENST00000368267
Interaction losses with Clinvar proteins
Gene Name