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Specific dMDT
Disease-type-specific MDTs
Lost Domain in dMDT
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Gene Name:
Transcript ID:
Transcript Name:
dMDT Interaction Network
Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name
Interaction Lost
Lost Domain (Region)
Lost Domain - Domain Interaction
SORBS2
SORBS2
-ABL1
SH3_1
(944-991)
SH3_1
(944-991) -
SH2
SORBS2
SORBS2
-PTK2B
SH3_1
(944-991)
SH3_1
(944-991) -
Pkinase_Tyr
Network Density Score:
%
The local network of this protein has more interaction than
% of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
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Sample ID
Disease Type
Gene Name 1
Gene Name 2
Transcript Name
dMDT
0f3ce1eb-6393-4c42-bd47-2cf67ba378ca
Skin.Skin-Melanoma
SORBS2
ABL1
SORBS2-051
ENST00000438278
0f3ce1eb-6393-4c42-bd47-2cf67ba378ca
Skin.Skin-Melanoma
SORBS2
PTK2B
SORBS2-051
ENST00000438278
2b6b5499-a092-4fb6-a670-ad599db4f2cb
Skin.Skin-Melanoma
SORBS2
ABL1
SORBS2-051
ENST00000438278
2b6b5499-a092-4fb6-a670-ad599db4f2cb
Skin.Skin-Melanoma
SORBS2
PTK2B
SORBS2-051
ENST00000438278
d17f1df8-d3de-4a01-930c-a066942e9fe4
Skin.Skin-Melanoma
SORBS2
ABL1
SORBS2-051
ENST00000438278
d17f1df8-d3de-4a01-930c-a066942e9fe4
Skin.Skin-Melanoma
SORBS2
PTK2B
SORBS2-051
ENST00000438278
df1c6f54-51a3-4a76-9ba7-281904144ffc
Skin.Skin-Melanoma
SORBS2
ABL1
SORBS2-051
ENST00000438278
df1c6f54-51a3-4a76-9ba7-281904144ffc
Skin.Skin-Melanoma
SORBS2
PTK2B
SORBS2-051
ENST00000438278
ec79139b-a1a8-4c38-9db6-b8570fb49a88
Skin.Skin-Melanoma
SORBS2
ABL1
SORBS2-051
ENST00000438278
ec79139b-a1a8-4c38-9db6-b8570fb49a88
Skin.Skin-Melanoma
SORBS2
PTK2B
SORBS2-051
ENST00000438278
7250c569-720a-49e4-a53e-20abfe9073dc
Stomach.Stomach-AdenoCA
SORBS2
ABL1
SORBS2-051
ENST00000438278
7250c569-720a-49e4-a53e-20abfe9073dc
Stomach.Stomach-AdenoCA
SORBS2
PTK2B
SORBS2-051
ENST00000438278
c6721c2d-adce-447c-83dd-e500b43506fc
Stomach.Stomach-AdenoCA
SORBS2
ABL1
SORBS2-051
ENST00000438278
c6721c2d-adce-447c-83dd-e500b43506fc
Stomach.Stomach-AdenoCA
SORBS2
PTK2B
SORBS2-051
ENST00000438278
Interaction losses with Clinvar proteins
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Gene Name
ABL1