CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
SPSB1 SPSB1-RASA1 SOCS_box(234-273) SOCS_box(234-273) - SH2
SPSB1 SPSB1-TCEB1 SOCS_box(234-273) SOCS_box(234-273) - Skp1_POZ

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA SPSB1 RASA1 SPSB1-004 ENST00000450402
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA SPSB1 TCEB1 SPSB1-004 ENST00000450402
Interaction losses with Clinvar proteins
Gene Name
RASA1