dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| SRPRB | SRPRB-RPL9 | GTP_EFTU(62-267) | GTP_EFTU(62-267) - Ribosomal_L6 |
| SRPRB | SRPRB-ARL3 | Arf(48-214) | Arf(48-214) - Arf |
| SRPRB | SRPRB-RPL10A | MMR_HSR1(66-199) | MMR_HSR1(66-199) - Ribosomal_L1 |
| SRPRB | SRPRB-RPS3 | MMR_HSR1(66-199) | MMR_HSR1(66-199) - KH_2 |
| SRPRB | SRPRB-RPL31 | SRPRB(62-241) | SRPRB(62-241) - Ribosomal_L31e |
| SRPRB | SRPRB-SRPR | SRPRB(62-241) | SRPRB(62-241) - SRP-alpha_N |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| SRR19243471 | Alzheimer's disease | SRPRB | RPL9 | SRPRB-003 | ENST00000484684 |
| SRR19243471 | Alzheimer's disease | SRPRB | ARL3 | SRPRB-003 | ENST00000484684 |
| SRR19243471 | Alzheimer's disease | SRPRB | RPL10A | SRPRB-003 | ENST00000484684 |
| SRR19243471 | Alzheimer's disease | SRPRB | RPS3 | SRPRB-003 | ENST00000484684 |
| SRR19243471 | Alzheimer's disease | SRPRB | RPL31 | SRPRB-003 | ENST00000484684 |
| SRR19243471 | Alzheimer's disease | SRPRB | SRPR | SRPRB-003 | ENST00000484684 |
Interaction losses with Clinvar proteins
| Gene Name |
|---|
| ARL3 |