CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
TOP2A TOP2A-TOP2B DNA_gyraseB(266-426) DNA_gyraseB(266-426) - DNA_gyraseB
TOP2A TOP2A-WRN Toprim(456-567) Toprim(456-567) - DEAD
TOP2A TOP2A-RECQL5 Toprim(456-567) Toprim(456-567) - DEAD
TOP2A TOP2A-BLM Toprim(456-567) Toprim(456-567) - DEAD
TOP2A TOP2A-RECQL Toprim(456-567) Toprim(456-567) - DEAD

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Interaction losses with Clinvar proteins
Gene Name
BLM
TOP2B
WRN