dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| TSG101 | TSG101-VPS28 | Vps23_core(315-379) | Vps23_core(315-379) - VPS28 |
| TSG101 | TSG101-VPS37B | Vps23_core(315-379) | Vps23_core(315-379) - Mod_r |
| TSG101 | TSG101-VPS37C | Vps23_core(315-379) | Vps23_core(315-379) - Mod_r |
| TSG101 | TSG101-VPS37A | Vps23_core(315-379) | Vps23_core(315-379) - Mod_r |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| SRR19243471 | Alzheimer's disease | TSG101 | VPS28 | TSG101-002 | ENST00000536719 |
| SRR19243471 | Alzheimer's disease | TSG101 | VPS37B | TSG101-002 | ENST00000536719 |
| SRR19243471 | Alzheimer's disease | TSG101 | VPS37C | TSG101-002 | ENST00000536719 |
| SRR19243471 | Alzheimer's disease | TSG101 | VPS37A | TSG101-002 | ENST00000536719 |
| SRR19243472 | Alzheimer's disease | TSG101 | VPS28 | TSG101-002 | ENST00000536719 |
| SRR19243472 | Alzheimer's disease | TSG101 | VPS37B | TSG101-002 | ENST00000536719 |
| SRR19243472 | Alzheimer's disease | TSG101 | VPS37C | TSG101-002 | ENST00000536719 |
| SRR19243472 | Alzheimer's disease | TSG101 | VPS37A | TSG101-002 | ENST00000536719 |
Interaction losses with Clinvar proteins
| Gene Name |
|---|
| VPS37A |