dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| TWF1 | TWF1-ACTC1 | Cofilin_ADF(197-294) | Cofilin_ADF(197-294) - Actin |
| TWF1 | TWF1-DSTN | Cofilin_ADF(197-294) | Cofilin_ADF(197-294) - Cofilin_ADF |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| SRR19243476 | Alzheimer's disease | TWF1 | ACTC1 | TWF1-008 | ENST00000550371 |
| SRR19243476 | Alzheimer's disease | TWF1 | DSTN | TWF1-008 | ENST00000550371 |
Interaction losses with Clinvar proteins
| Gene Name |
|---|
| ACTC1 |