CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
TXN TXN-NFKB1 Thioredoxin(6-103) Thioredoxin(6-103) - RHD
TXN TXN-PRDX1 Thioredoxin(6-103) Thioredoxin(6-103) - AhpC-TSA
TXN TXN-PRDX3 Thioredoxin(6-103) Thioredoxin(6-103) - AhpC-TSA
TXN TXN-PRDX2 Thioredoxin(6-103) Thioredoxin(6-103) - AhpC-TSA
TXN TXN-GSR Thioredoxin(6-103) Thioredoxin(6-103) - Pyr_redox_dim
TXN TXN-TXNRD2 Thioredoxin(6-103) Thioredoxin(6-103) - Pyr_redox_dim
TXN TXN-TXNRD3 Thioredoxin(6-103) Thioredoxin(6-103) - Pyr_redox_dim
TXN TXN-TXNRD1 Thioredoxin(6-103) Thioredoxin(6-103) - Pyr_redox_dim

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA TXN NFKB1 TXN-002 ENST00000374515
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA TXN PRDX1 TXN-002 ENST00000374515
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA TXN PRDX3 TXN-002 ENST00000374515
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA TXN PRDX2 TXN-002 ENST00000374515
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA TXN GSR TXN-002 ENST00000374515
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA TXN TXNRD2 TXN-002 ENST00000374515
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA TXN TXNRD3 TXN-002 ENST00000374515
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA TXN TXNRD1 TXN-002 ENST00000374515
Interaction losses with Clinvar proteins
Gene Name
GSR
NFKB1
PRDX1
PRDX3
TXNRD2