CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
UBE2M UBE2M-NEDD8 UQ_con(33-167) UQ_con(33-167) - ubiquitin
UBE2M UBE2M-UBC UQ_con(33-167) UQ_con(33-167) - ubiquitin
UBE2M UBE2M-CBL UQ_con(33-167) UQ_con(33-167) - UBA
UBE2M UBE2M-NAE1 UQ_con(33-167) UQ_con(33-167) - ThiF
UBE2M UBE2M-UBA3 UQ_con(33-167) UQ_con(33-167) - ThiF
UBE2M UBE2M-CUL1 UQ_con(33-167) UQ_con(33-167) - Cullin_Nedd8
UBE2M UBE2M-RBX1 UQ_con(33-167) UQ_con(33-167) - zf-rbx1

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
c400332b-7ef2-4891-8070-413cb48a7e9c Blood.Lymph-CLL UBE2M NEDD8 UBE2M-006 ENST00000595957
c400332b-7ef2-4891-8070-413cb48a7e9c Blood.Lymph-CLL UBE2M UBC UBE2M-006 ENST00000595957
c400332b-7ef2-4891-8070-413cb48a7e9c Blood.Lymph-CLL UBE2M CBL UBE2M-006 ENST00000595957
c400332b-7ef2-4891-8070-413cb48a7e9c Blood.Lymph-CLL UBE2M NAE1 UBE2M-006 ENST00000595957
c400332b-7ef2-4891-8070-413cb48a7e9c Blood.Lymph-CLL UBE2M UBA3 UBE2M-006 ENST00000595957
c400332b-7ef2-4891-8070-413cb48a7e9c Blood.Lymph-CLL UBE2M CUL1 UBE2M-006 ENST00000595957
c400332b-7ef2-4891-8070-413cb48a7e9c Blood.Lymph-CLL UBE2M RBX1 UBE2M-006 ENST00000595957
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA UBE2M NEDD8 UBE2M-006 ENST00000595957
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA UBE2M UBC UBE2M-006 ENST00000595957
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA UBE2M CBL UBE2M-006 ENST00000595957
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA UBE2M NAE1 UBE2M-006 ENST00000595957
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA UBE2M UBA3 UBE2M-006 ENST00000595957
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA UBE2M CUL1 UBE2M-006 ENST00000595957
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA UBE2M RBX1 UBE2M-006 ENST00000595957
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma UBE2M NEDD8 UBE2M-006 ENST00000595957
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma UBE2M UBC UBE2M-006 ENST00000595957
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma UBE2M CBL UBE2M-006 ENST00000595957
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma UBE2M NAE1 UBE2M-006 ENST00000595957
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma UBE2M UBA3 UBE2M-006 ENST00000595957
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma UBE2M CUL1 UBE2M-006 ENST00000595957
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma UBE2M RBX1 UBE2M-006 ENST00000595957
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma UBE2M NEDD8 UBE2M-006 ENST00000595957
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma UBE2M UBC UBE2M-006 ENST00000595957
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma UBE2M CBL UBE2M-006 ENST00000595957
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma UBE2M NAE1 UBE2M-006 ENST00000595957
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma UBE2M UBA3 UBE2M-006 ENST00000595957
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma UBE2M CUL1 UBE2M-006 ENST00000595957
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma UBE2M RBX1 UBE2M-006 ENST00000595957
Interaction losses with Clinvar proteins
Gene Name
CBL