CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
WNK4 None None None
WNK4 WNK4-STK39 Pkinase(179-432) Pkinase(179-432) - Pkinase
WNK4 WNK4-RPS27A Pkinase(179-432) Pkinase(179-432) - ubiquitin
WNK4 WNK4-UBB Pkinase(179-432) Pkinase(179-432) - ubiquitin
WNK4 WNK4-UBC Pkinase(179-432) Pkinase(179-432) - ubiquitin
WNK4 WNK4-UBA52 Pkinase(179-432) Pkinase(179-432) - ubiquitin
WNK4 WNK4-ITSN1 Pkinase_Tyr(174-430) Pkinase_Tyr(174-430) - SH3_9

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
ef37a73c-e0a0-4ff6-83a3-6befcdcb51c6 Breast.Breast-AdenoCA WNK4 None WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 STK39 WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 RPS27A WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 UBB WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 UBC WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 UBA52 WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 ITSN1 WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 STK39 WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 RPS27A WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 UBB WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 UBC WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 UBA52 WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 ITSN1 WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 STK39 WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 RPS27A WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 UBB WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 UBC WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 UBA52 WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 ITSN1 WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 STK39 WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 RPS27A WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 UBB WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 UBC WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 UBA52 WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 ITSN1 WNK4-002 ENST00000591448
Interaction losses with Clinvar proteins
Gene Name
WNK4