dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| RAF1 | RAF1-PRKG1 | Pkinase(349-606) | Pkinase(349-606) - cNMP_binding |
| RAF1 | RAF1-RAPGEF3 | Pkinase(349-606) | Pkinase(349-606) - cNMP_binding |
| RAF1 | RAF1-RAPGEF4 | Pkinase(349-606) | Pkinase(349-606) - cNMP_binding |
| RAF1 | RAF1-IGF1R | Pkinase(349-606) | Pkinase(349-606) - fn3 |
| RAF1 | RAF1-MAPK1 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-MAP2K2 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-MAPK3 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-AKT1 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-PAK1 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-BRAF | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-MAP2K1 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-PRKCB | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-PRKCE | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-PRKACA | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-PAK2 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-CAMK2G | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-KSR1 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-PRKCD | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-CAMK2D | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-SGK2 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-PAK4 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-PAK3 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-SGK1 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-PRKCZ | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-CAMK2B | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-CAMK2A | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-STK3 | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-PRKCA | Pkinase(349-606) | Pkinase(349-606) - Pkinase |
| RAF1 | RAF1-RRAS | Pkinase(349-606) | Pkinase(349-606) - Ras |
| RAF1 | RAF1-RAP1B | Pkinase(349-606) | Pkinase(349-606) - Ras |
| RAF1 | RAF1-KRAS | Pkinase(349-606) | Pkinase(349-606) - Ras |
| RAF1 | RAF1-RRAS2 | Pkinase(349-606) | Pkinase(349-606) - Ras |
| RAF1 | RAF1-RHEB | Pkinase(349-606) | Pkinase(349-606) - Ras |
| RAF1 | RAF1-MRAS | Pkinase(349-606) | Pkinase(349-606) - Ras |
| RAF1 | RAF1-HRAS | Pkinase(349-606) | Pkinase(349-606) - Ras |
| RAF1 | RAF1-RAP1A | Pkinase(349-606) | Pkinase(349-606) - Ras |
| RAF1 | RAF1-NRAS | Pkinase(349-606) | Pkinase(349-606) - Ras |
| RAF1 | RAF1-RHOA | Pkinase(349-606) | Pkinase(349-606) - Ras |
| RAF1 | RAF1-RASGRP1 | Pkinase(349-606) | Pkinase(349-606) - C1_1 |
| RAF1 | RAF1-RASGRP2 | Pkinase(349-606) | Pkinase(349-606) - C1_1 |
| RAF1 | RAF1-CCND1 | Pkinase(349-606) | Pkinase(349-606) - Cyclin_N |
| RAF1 | RAF1-RASA1 | Pkinase(349-606) | Pkinase(349-606) - PH |
| RAF1 | RAF1-CNKSR1 | Pkinase(349-606) | Pkinase(349-606) - PH |
| RAF1 | RAF1-DNM1 | Pkinase(349-606) | Pkinase(349-606) - PH |
| RAF1 | RAF1-CNKSR2 | Pkinase(349-606) | Pkinase(349-606) - PH |
| RAF1 | RAF1-GRB10 | Pkinase(349-606) | Pkinase(349-606) - PH |
| RAF1 | RAF1-HSP90AB1 | Pkinase(349-606) | Pkinase(349-606) - HSP90 |
| RAF1 | RAF1-HSP90AA1 | Pkinase(349-606) | Pkinase(349-606) - HSP90 |
| RAF1 | RAF1-RPS27A | Pkinase(349-606) | Pkinase(349-606) - ubiquitin |
| RAF1 | RAF1-UBB | Pkinase(349-606) | Pkinase(349-606) - ubiquitin |
| RAF1 | RAF1-UBC | Pkinase(349-606) | Pkinase(349-606) - ubiquitin |
| RAF1 | RAF1-UBA52 | Pkinase(349-606) | Pkinase(349-606) - ubiquitin |
| RAF1 | RAF1-BAG1 | Pkinase(349-606) | Pkinase(349-606) - ubiquitin |
| RAF1 | RAF1-DUSP1 | Pkinase(349-606) | Pkinase(349-606) - Rhodanese |
| RAF1 | RAF1-CDC25A | Pkinase(349-606) | Pkinase(349-606) - Rhodanese |
| RAF1 | RAF1-CDKN1A | Pkinase(349-606) | Pkinase(349-606) - CDI |
| RAF1 | RAF1-CDC37 | Pkinase(349-606) | Pkinase(349-606) - CDC37_N |
| RAF1 | RAF1-PDGFRB | Pkinase(349-606) | Pkinase(349-606) - I-set |
| RAF1 | RAF1-SRC | Pkinase(349-606) | Pkinase(349-606) - Pkinase_Tyr |
| RAF1 | RAF1-STAT3 | C1_1(139-185) | C1_1(139-185) - SH2 |
| RAF1 | RAF1-STAT2 | C1_1(139-185) | C1_1(139-185) - SH2 |
| RAF1 | RAF1-INPP5D | C1_1(139-185) | C1_1(139-185) - SH2 |
| RAF1 | RAF1-STAT1 | C1_1(139-185) | C1_1(139-185) - SH2 |
| RAF1 | RAF1-WWP1 | C1_1(139-185) | C1_1(139-185) - C2 |
| RAF1 | RAF1-NEDD4L | C1_1(139-185) | C1_1(139-185) - C2 |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch