CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
EIF4A1 9 9 EIF4A1-DHX8 DEAD(57-222)-DEAD EIF4A1-032 ENST00000582050
EIF4A1 9 9 EIF4A1-EIF4A3 DEAD(57-222)-DEAD EIF4A1-032 ENST00000582050
EIF4A1 9 9 EIF4A1-EIF4A2 DEAD(57-222)-DEAD EIF4A1-032 ENST00000582050
EIF4A1 9 9 EIF4A1-RPL36 DEAD(57-222)-Ribosomal_L36e EIF4A1-032 ENST00000582050
EIF4A1 9 9 EIF4A1-PDCD4 DEAD(57-222)-MA3 EIF4A1-032 ENST00000582050
EIF4A1 9 9 EIF4A1-EIF4G1 DEAD(57-222)-MA3 EIF4A1-032 ENST00000582050
EIF4A1 9 9 EIF4A1-EIF4G2 DEAD(57-222)-MA3 EIF4A1-032 ENST00000582050
EIF4A1 9 9 EIF4A1-PAIP1 DEAD(57-222)-MIF4G EIF4A1-032 ENST00000582050
EIF4A1 9 9 EIF4A1-RPL10A Helicase_C(292-367)-Ribosomal_L1 EIF4A1-032 ENST00000582050
EIF4A1 9 9 EIF4A1-DHX8 DEAD(57-222)-DEAD EIF4A1-004 ENST00000581544
EIF4A1 9 9 EIF4A1-EIF4A3 DEAD(57-222)-DEAD EIF4A1-004 ENST00000581544
EIF4A1 9 9 EIF4A1-EIF4A2 DEAD(57-222)-DEAD EIF4A1-004 ENST00000581544
EIF4A1 9 9 EIF4A1-RPL36 DEAD(57-222)-Ribosomal_L36e EIF4A1-004 ENST00000581544
EIF4A1 9 9 EIF4A1-PDCD4 DEAD(57-222)-MA3 EIF4A1-004 ENST00000581544
EIF4A1 9 9 EIF4A1-EIF4G1 DEAD(57-222)-MA3 EIF4A1-004 ENST00000581544
EIF4A1 9 9 EIF4A1-EIF4G2 DEAD(57-222)-MA3 EIF4A1-004 ENST00000581544
EIF4A1 9 9 EIF4A1-PAIP1 DEAD(57-222)-MIF4G EIF4A1-004 ENST00000581544
EIF4A1 9 9 EIF4A1-RPL10A Helicase_C(292-367)-Ribosomal_L1 EIF4A1-004 ENST00000581544

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC EIF4A1 DHX8 EIF4A1-032 ENST00000582050
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC EIF4A1 EIF4A3 EIF4A1-032 ENST00000582050
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC EIF4A1 EIF4A2 EIF4A1-032 ENST00000582050
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC EIF4A1 RPL36 EIF4A1-032 ENST00000582050
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC EIF4A1 PDCD4 EIF4A1-032 ENST00000582050
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC EIF4A1 EIF4G1 EIF4A1-032 ENST00000582050
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC EIF4A1 EIF4G2 EIF4A1-032 ENST00000582050
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC EIF4A1 PAIP1 EIF4A1-032 ENST00000582050
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC EIF4A1 RPL10A EIF4A1-032 ENST00000582050
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA EIF4A1 DHX8 EIF4A1-004 ENST00000581544
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA EIF4A1 EIF4A3 EIF4A1-004 ENST00000581544
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA EIF4A1 EIF4A2 EIF4A1-004 ENST00000581544
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA EIF4A1 RPL36 EIF4A1-004 ENST00000581544
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA EIF4A1 PDCD4 EIF4A1-004 ENST00000581544
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA EIF4A1 EIF4G1 EIF4A1-004 ENST00000581544
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA EIF4A1 EIF4G2 EIF4A1-004 ENST00000581544
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA EIF4A1 PAIP1 EIF4A1-004 ENST00000581544
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA EIF4A1 RPL10A EIF4A1-004 ENST00000581544
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA EIF4A1 DHX8 EIF4A1-032 ENST00000582050
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA EIF4A1 EIF4A3 EIF4A1-032 ENST00000582050
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA EIF4A1 EIF4A2 EIF4A1-032 ENST00000582050
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA EIF4A1 RPL36 EIF4A1-032 ENST00000582050
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA EIF4A1 PDCD4 EIF4A1-032 ENST00000582050
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA EIF4A1 EIF4G1 EIF4A1-032 ENST00000582050
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA EIF4A1 EIF4G2 EIF4A1-032 ENST00000582050
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA EIF4A1 PAIP1 EIF4A1-032 ENST00000582050
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA EIF4A1 RPL10A EIF4A1-032 ENST00000582050
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA EIF4A1 DHX8 EIF4A1-032 ENST00000582050
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA EIF4A1 EIF4A3 EIF4A1-032 ENST00000582050
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA EIF4A1 EIF4A2 EIF4A1-032 ENST00000582050
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA EIF4A1 RPL36 EIF4A1-032 ENST00000582050
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA EIF4A1 PDCD4 EIF4A1-032 ENST00000582050
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA EIF4A1 EIF4G1 EIF4A1-032 ENST00000582050
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA EIF4A1 EIF4G2 EIF4A1-032 ENST00000582050
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA EIF4A1 PAIP1 EIF4A1-032 ENST00000582050
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA EIF4A1 RPL10A EIF4A1-032 ENST00000582050
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA EIF4A1 DHX8 EIF4A1-032 ENST00000582050
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA EIF4A1 EIF4A3 EIF4A1-032 ENST00000582050
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA EIF4A1 EIF4A2 EIF4A1-032 ENST00000582050
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA EIF4A1 RPL36 EIF4A1-032 ENST00000582050
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA EIF4A1 PDCD4 EIF4A1-032 ENST00000582050
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA EIF4A1 EIF4G1 EIF4A1-032 ENST00000582050
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA EIF4A1 EIF4G2 EIF4A1-032 ENST00000582050
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA EIF4A1 PAIP1 EIF4A1-032 ENST00000582050
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA EIF4A1 RPL10A EIF4A1-032 ENST00000582050
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA EIF4A1 DHX8 EIF4A1-032 ENST00000582050
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA EIF4A1 EIF4A3 EIF4A1-032 ENST00000582050
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA EIF4A1 EIF4A2 EIF4A1-032 ENST00000582050
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA EIF4A1 RPL36 EIF4A1-032 ENST00000582050
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA EIF4A1 PDCD4 EIF4A1-032 ENST00000582050
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA EIF4A1 EIF4G1 EIF4A1-032 ENST00000582050
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA EIF4A1 EIF4G2 EIF4A1-032 ENST00000582050
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA EIF4A1 PAIP1 EIF4A1-032 ENST00000582050
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA EIF4A1 RPL10A EIF4A1-032 ENST00000582050