CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
PBX1 13 0 None None PBX1-002 ENST00000367897
PBX1 13 13 PBX1-HOXA5 Homeobox(234-293)-Homeobox PBX1-012 ENST00000559240
PBX1 13 13 PBX1-NANOG Homeobox(234-293)-Homeobox PBX1-012 ENST00000559240
PBX1 13 13 PBX1-HOXB5 Homeobox(234-293)-Homeobox PBX1-012 ENST00000559240
PBX1 13 13 PBX1-HOXB7 Homeobox(234-293)-Homeobox PBX1-012 ENST00000559240
PBX1 13 13 PBX1-HOXD10 Homeobox(234-293)-Homeobox PBX1-012 ENST00000559240
PBX1 13 13 PBX1-POU5F1 Homeobox(234-293)-Homeobox PBX1-012 ENST00000559240
PBX1 13 13 PBX1-HOXA10 Homeobox(234-293)-Homeobox PBX1-012 ENST00000559240
PBX1 13 13 PBX1-HOXA9 Homeobox(234-293)-Homeobox PBX1-012 ENST00000559240
PBX1 13 13 PBX1-HOXB1 Homeobox(234-293)-Homeobox PBX1-012 ENST00000559240
PBX1 13 13 PBX1-MEIS1 Homeobox(234-293)-Homeobox_KN PBX1-012 ENST00000559240
PBX1 13 13 PBX1-PKNOX1 Homeobox(234-293)-Homeobox_KN PBX1-012 ENST00000559240
PBX1 13 13 PBX1-MEIS3 Homeobox(234-293)-Homeobox_KN PBX1-012 ENST00000559240
PBX1 13 13 PBX1-MEIS2 Homeobox(234-293)-Homeobox_KN PBX1-012 ENST00000559240
PBX1 13 13 PBX1-HOXA5 Homeobox(234-293)-Homeobox PBX1-006 ENST00000485769
PBX1 13 13 PBX1-NANOG Homeobox(234-293)-Homeobox PBX1-006 ENST00000485769
PBX1 13 13 PBX1-HOXB5 Homeobox(234-293)-Homeobox PBX1-006 ENST00000485769
PBX1 13 13 PBX1-HOXB7 Homeobox(234-293)-Homeobox PBX1-006 ENST00000485769
PBX1 13 13 PBX1-HOXD10 Homeobox(234-293)-Homeobox PBX1-006 ENST00000485769
PBX1 13 13 PBX1-POU5F1 Homeobox(234-293)-Homeobox PBX1-006 ENST00000485769
PBX1 13 13 PBX1-HOXA10 Homeobox(234-293)-Homeobox PBX1-006 ENST00000485769
PBX1 13 13 PBX1-HOXA9 Homeobox(234-293)-Homeobox PBX1-006 ENST00000485769
PBX1 13 13 PBX1-HOXB1 Homeobox(234-293)-Homeobox PBX1-006 ENST00000485769
PBX1 13 13 PBX1-MEIS1 Homeobox(234-293)-Homeobox_KN PBX1-006 ENST00000485769
PBX1 13 13 PBX1-PKNOX1 Homeobox(234-293)-Homeobox_KN PBX1-006 ENST00000485769
PBX1 13 13 PBX1-MEIS3 Homeobox(234-293)-Homeobox_KN PBX1-006 ENST00000485769
PBX1 13 13 PBX1-MEIS2 Homeobox(234-293)-Homeobox_KN PBX1-006 ENST00000485769

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA PBX1 - PBX1-002 ENST00000367897
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA PBX1 - PBX1-002 ENST00000367897
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 HOXA5 PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 NANOG PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 HOXB5 PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 HOXB7 PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 HOXD10 PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 POU5F1 PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 HOXA10 PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 HOXA9 PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 HOXB1 PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 MEIS1 PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 PKNOX1 PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 MEIS3 PBX1-012 ENST00000559240
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PBX1 MEIS2 PBX1-012 ENST00000559240
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 HOXA5 PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 NANOG PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 HOXB5 PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 HOXB7 PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 HOXD10 PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 POU5F1 PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 HOXA10 PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 HOXA9 PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 HOXB1 PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 MEIS1 PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 PKNOX1 PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 MEIS3 PBX1-006 ENST00000485769
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA PBX1 MEIS2 PBX1-006 ENST00000485769
c60df680-5bd6-48cc-a112-985f73d9092c Uterus.Uterus-AdenoCA PBX1 - PBX1-002 ENST00000367897