CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name
# of
Interaction*
# of Missed
Interaction
Interaction
Lost
Domain Int
Lost
Transcript Name dMDT
PLEKHG6 1 1 PLEKHG6-RHOA RhoGEF(166-351)-Ras PLEKHG6-005 ENST00000304581
PLEKHG6 1 0 None None PLEKHG6-001 ENST00000011684

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
357ba9f6-716c-4ef0-8ac8-41977397dbf5 Breast.Breast-AdenoCA PLEKHG6 RHOA PLEKHG6-005 ENST00000304581
ef37a73c-e0a0-4ff6-83a3-6befcdcb51c6 Breast.Breast-AdenoCA PLEKHG6 RHOA PLEKHG6-005 ENST00000304581
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
1857cddd-76d1-403b-a14e-f14d0781f68b Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
2fc92e79-f56f-46b9-b378-a242dd7642d6 Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
39dbc57b-dd7d-4ebe-a905-47b500adef88 Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
43abe272-41cb-4b54-b6f6-50a27c670e46 Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
4575ca5e-968c-419d-9707-4e99d55dddb7 Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
543b9907-bf2a-4f64-b83f-13cc4289310b Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
5706f1b9-2c2c-4906-a9fb-64ba5a57d47e Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
8e901591-a236-4208-899b-f1bde1e5f841 Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
9cde3009-e59c-4a08-bd85-e3f5ab521d41 Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
a2d46b53-d9bd-4c19-9a0a-fecb48d3c06a Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
b280c179-336d-4638-9309-0f51426f8054 Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
bd558781-2e3b-4fb0-aeb8-a8cefbf3272d Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
c60df680-5bd6-48cc-a112-985f73d9092c Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
ca1e32b0-7daf-403e-a3b2-7cfd3948cedf Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
cbd18c2a-4544-4a90-904e-533c3f776f32 Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
de485b7d-cd88-4889-aff4-e290027f26bb Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
deeb2238-8ed6-4651-8b63-428c76914c94 Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684
fcb43e1a-3b34-4ff1-8d3e-849fbf901877 Uterus.Uterus-AdenoCA PLEKHG6 - PLEKHG6-001 ENST00000011684