CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
POLR1D 13 13 POLR1D-ERCC3 RNA_pol_L(40-108)-Helicase_C POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-ERCC6 RNA_pol_L(40-108)-Helicase_C POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-CHD4 RNA_pol_L(40-108)-Helicase_C POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-CHD3 RNA_pol_L(40-108)-Helicase_C POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-POLR3B RNA_pol_L(40-108)-RNA_pol_Rpb2_6 POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-POLR1B RNA_pol_L(40-108)-RNA_pol_Rpb2_6 POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-POLR1A RNA_pol_L(40-108)-RNA_pol_Rpb1_2 POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-POLR3A RNA_pol_L(40-108)-RNA_pol_Rpb1_2 POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-POLR2F RNA_pol_L(40-108)-RNA_pol_Rpb6 POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-POLR2C RNA_pol_L(40-108)-RNA_pol_L POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-POLR1C RNA_pol_L(40-108)-RNA_pol_L POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-POLR2L RNA_pol_L(40-108)-RNA_pol_N POLR1D-004 ENST00000399697
POLR1D 13 13 POLR1D-POLR2K RNA_pol_L(40-108)-DNA_RNApol_7kD POLR1D-004 ENST00000399697

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D ERCC3 POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D ERCC6 POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D CHD4 POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D CHD3 POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D POLR3B POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D POLR1B POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D POLR1A POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D POLR3A POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D POLR2F POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D POLR2C POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D POLR1C POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D POLR2L POLR1D-004 ENST00000399697
f66ad0c1-2663-4f0d-80b0-fbdb6a94e607 Kidney.Kidney-RCC POLR1D POLR2K POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D ERCC3 POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D ERCC6 POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D CHD4 POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D CHD3 POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D POLR3B POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D POLR1B POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D POLR1A POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D POLR3A POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D POLR2F POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D POLR2C POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D POLR1C POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D POLR2L POLR1D-004 ENST00000399697
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA POLR1D POLR2K POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D ERCC3 POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D ERCC6 POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D CHD4 POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D CHD3 POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D POLR3B POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D POLR1B POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D POLR1A POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D POLR3A POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D POLR2F POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D POLR2C POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D POLR1C POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D POLR2L POLR1D-004 ENST00000399697
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA POLR1D POLR2K POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D ERCC3 POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D ERCC6 POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D CHD4 POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D CHD3 POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D POLR3B POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D POLR1B POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D POLR1A POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D POLR3A POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D POLR2F POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D POLR2C POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D POLR1C POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D POLR2L POLR1D-004 ENST00000399697
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA POLR1D POLR2K POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D ERCC3 POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D ERCC6 POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D CHD4 POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D CHD3 POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D POLR3B POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D POLR1B POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D POLR1A POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D POLR3A POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D POLR2F POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D POLR2C POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D POLR1C POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D POLR2L POLR1D-004 ENST00000399697
553e71f7-3c4a-4f58-b953-1c6ee8422f02 Pancreas.Panc-AdenoCA POLR1D POLR2K POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D ERCC3 POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D ERCC6 POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D CHD4 POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D CHD3 POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D POLR3B POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D POLR1B POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D POLR1A POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D POLR3A POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D POLR2F POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D POLR2C POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D POLR1C POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D POLR2L POLR1D-004 ENST00000399697
A8AE9773-3287-43E4-A18A-1ACE7291E83F Thyroid.Thy-AdenoCA POLR1D POLR2K POLR1D-004 ENST00000399697