dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| C4A | C4A-C4BPB | A2M(782-869) | A2M(782-869) - Sushi |
| C4A | C4A-CD46 | A2M(782-869) | A2M(782-869) - Sushi |
| C4A | C4A-CR1 | A2M(782-869) | A2M(782-869) - Sushi |
| C4A | C4A-C4BPA | A2M(782-869) | A2M(782-869) - Sushi |
| C4A | C4A-MASP2 | A2M(782-869) | A2M(782-869) - Sushi |
| C4A | C4A-C3 | A2M(782-869) | A2M(782-869) - A2M_N |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| f3ead589-7559-40f1-b7de-9a5bb62931a6 | Pancreas.Panc-AdenoCA | C4A | C4BPB | C4A-204 | ENST00000537134 |
| f3ead589-7559-40f1-b7de-9a5bb62931a6 | Pancreas.Panc-AdenoCA | C4A | CD46 | C4A-204 | ENST00000537134 |
| f3ead589-7559-40f1-b7de-9a5bb62931a6 | Pancreas.Panc-AdenoCA | C4A | CR1 | C4A-204 | ENST00000537134 |
| f3ead589-7559-40f1-b7de-9a5bb62931a6 | Pancreas.Panc-AdenoCA | C4A | C4BPA | C4A-204 | ENST00000537134 |
| f3ead589-7559-40f1-b7de-9a5bb62931a6 | Pancreas.Panc-AdenoCA | C4A | MASP2 | C4A-204 | ENST00000537134 |
| f3ead589-7559-40f1-b7de-9a5bb62931a6 | Pancreas.Panc-AdenoCA | C4A | C3 | C4A-204 | ENST00000537134 |