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Specific dMDT
Disease-type-specific MDTs
Lost Domain in dMDT
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Gene Name:
Transcript ID:
Transcript Name:
dMDT Interaction Network
Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name
Interaction Lost
Lost Domain (Region)
Lost Domain - Domain Interaction
G3BP1
G3BP1
-PDPK1
RRM_1
(342-396)
RRM_1
(342-396) -
Pkinase
G3BP1
G3BP1
-TARDBP
RRM_1
(342-396)
RRM_1
(342-396) -
RRM_1
Network Density Score:
%
The local network of this protein has more interaction than
% of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
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Sample ID
Disease Type
Gene Name 1
Gene Name 2
Transcript Name
dMDT
1d43f7a5-43ac-4861-b4a7-7bfce13ac2c5
Kidney.Kidney-RCC
G3BP1
PDPK1
G3BP1-006
ENST00000520177
1d43f7a5-43ac-4861-b4a7-7bfce13ac2c5
Kidney.Kidney-RCC
G3BP1
TARDBP
G3BP1-006
ENST00000520177
76733f6c-f1c1-4d57-bf7d-87640d3b88f9
Muscle.Bone-Leiomyo
G3BP1
PDPK1
G3BP1-006
ENST00000520177
76733f6c-f1c1-4d57-bf7d-87640d3b88f9
Muscle.Bone-Leiomyo
G3BP1
TARDBP
G3BP1-006
ENST00000520177
bbff8493-879b-4fa2-8bca-ea5160764e4a
Muscle.Bone-Leiomyo
G3BP1
PDPK1
G3BP1-006
ENST00000520177
bbff8493-879b-4fa2-8bca-ea5160764e4a
Muscle.Bone-Leiomyo
G3BP1
TARDBP
G3BP1-006
ENST00000520177
fef90a5d-49de-4277-a927-e6cfe7b3936e
Muscle.Bone-Leiomyo
G3BP1
PDPK1
G3BP1-006
ENST00000520177
fef90a5d-49de-4277-a927-e6cfe7b3936e
Muscle.Bone-Leiomyo
G3BP1
TARDBP
G3BP1-006
ENST00000520177
Interaction losses with Clinvar proteins
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Gene Name
TARDBP