CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
HADHB HADHB-ACAT1 Thiolase_N(52-324) Thiolase_N(52-324) - Thiolase_N
HADHB HADHB-ACAT2 Thiolase_N(52-324) Thiolase_N(52-324) - Thiolase_N
HADHB HADHB-EHHADH Thiolase_N(52-324) Thiolase_N(52-324) - ECH
HADHB HADHB-ECI1 Thiolase_N(52-324) Thiolase_N(52-324) - ECH
HADHB HADHB-ECHS1 Thiolase_N(52-324) Thiolase_N(52-324) - ECH
HADHB HADHB-HADHA Thiolase_N(52-324) Thiolase_N(52-324) - ECH
HADHB HADHB-ECHDC1 Thiolase_N(52-324) Thiolase_N(52-324) - ECH

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHB ACAT1 HADHB-002 ENST00000405867
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHB ACAT2 HADHB-002 ENST00000405867
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHB EHHADH HADHB-002 ENST00000405867
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHB ECI1 HADHB-002 ENST00000405867
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHB ECHS1 HADHB-002 ENST00000405867
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHB HADHA HADHB-002 ENST00000405867
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHB ECHDC1 HADHB-002 ENST00000405867
Interaction losses with Clinvar proteins
Gene Name
ACAT1
ACAT2
ECHS1
EHHADH
HADHA
HADHB