dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| HAND2 | HAND2-HAND1 | HLH(100-151) | HLH(100-151) - HLH |
| HAND2 | HAND2-TCF3 | HLH(100-151) | HLH(100-151) - HLH |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| b2ee51d4-301a-47f2-9be0-de43df53cad6 | Colon.ColoRect-AdenoCA | HAND2 | HAND1 | HAND2-006 | ENST00000503024 |
| b2ee51d4-301a-47f2-9be0-de43df53cad6 | Colon.ColoRect-AdenoCA | HAND2 | TCF3 | HAND2-006 | ENST00000503024 |
| 8027afbd-234f-4911-b193-880741f216d4 | Pancreas.Panc-AdenoCA | HAND2 | HAND1 | HAND2-006 | ENST00000503024 |
| 8027afbd-234f-4911-b193-880741f216d4 | Pancreas.Panc-AdenoCA | HAND2 | TCF3 | HAND2-006 | ENST00000503024 |
| ea84deee-d0be-49e7-b451-9d0c3d6361fb | Pancreas.Panc-AdenoCA | HAND2 | HAND1 | HAND2-006 | ENST00000503024 |
| ea84deee-d0be-49e7-b451-9d0c3d6361fb | Pancreas.Panc-AdenoCA | HAND2 | TCF3 | HAND2-006 | ENST00000503024 |
Interaction losses with Clinvar proteins
| Gene Name |
|---|
| TCF3 |