CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
HIF3A HIF3A-ARNT PAS(92-146) PAS(92-146) - HLH
HIF3A HIF3A-EPAS1 PAS(92-146) PAS(92-146) - PAS
HIF3A HIF3A-HIF1A PAS(92-146) PAS(92-146) - PAS
HIF3A HIF3A-VHL HIF-1(478-509) HIF-1(478-509) - VHL
HIF3A HIF3A-EGLN3 HIF-1(478-509) HIF-1(478-509) - 2OG-FeII_Oxy_3
HIF3A HIF3A-EGLN2 HIF-1(478-509) HIF-1(478-509) - 2OG-FeII_Oxy_3
HIF3A HIF3A-EGLN1 HIF-1(478-509) HIF-1(478-509) - 2OG-FeII_Oxy_3

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Interaction losses with Clinvar proteins
Gene Name
EGLN1
EPAS1
VHL