CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
HLA-DQB1 HLA-DQB1-HLA-DQA1 MHC_II_beta(46-117) MHC_II_beta(46-117) - MHC_II_alpha

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
429f0e9d-c160-4b36-a31b-dab1097c6129 Bladder.Bladder-TCC HLA-DQB1 HLA-DQA1 HLA-DQB1-007 ENST00000399082
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC HLA-DQB1 HLA-DQA1 HLA-DQB1-007 ENST00000399082
50db517a-a5c7-431e-9439-cb5cffb9b954 Kidney.Kidney-RCC HLA-DQB1 HLA-DQA1 HLA-DQB1-007 ENST00000399082
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC HLA-DQB1 HLA-DQA1 HLA-DQB1-007 ENST00000399082
56e6f602-0afb-434e-b28e-665d923ad781 Liver.Liver-HCC HLA-DQB1 HLA-DQA1 HLA-DQB1-007 ENST00000399082
5bd6ca42-16ca-484f-877f-cda4fb3f93a8 Liver.Liver-HCC HLA-DQB1 HLA-DQA1 HLA-DQB1-007 ENST00000399082
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA HLA-DQB1 HLA-DQA1 HLA-DQB1-007 ENST00000399082
358984cc-b532-4f00-89f4-dda524469b6d Ovary.Ovary-AdenoCA HLA-DQB1 HLA-DQA1 HLA-DQB1-007 ENST00000399082
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA HLA-DQB1 HLA-DQA1 HLA-DQB1-007 ENST00000399082
ee665717-a903-44bc-8eaa-afb46bd4edf0 Thyroid.Thy-AdenoCA HLA-DQB1 HLA-DQA1 HLA-DQB1-007 ENST00000399082
Interaction losses with Clinvar proteins
Gene Name
HLA-DQA1
HLA-DQB1