dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| IFNGR1 | IFNGR1-IFNG | Tissue_fac(7-112) | Tissue_fac(7-112) - IFN-gamma |
| IFNGR1 | IFNGR1-SIRPB1 | Tissue_fac(7-112) | Tissue_fac(7-112) - V-set |
| IFNGR1 | IFNGR1-IFNGR2 | Tissue_fac(7-112) | Tissue_fac(7-112) - Interfer-bind |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| 82bb01e9-a659-417b-b9e8-831a76277a21 | Colon.ColoRect-AdenoCA | IFNGR1 | IFNG | IFNGR1-002 | ENST00000458076 |
| 82bb01e9-a659-417b-b9e8-831a76277a21 | Colon.ColoRect-AdenoCA | IFNGR1 | SIRPB1 | IFNGR1-002 | ENST00000458076 |
| 82bb01e9-a659-417b-b9e8-831a76277a21 | Colon.ColoRect-AdenoCA | IFNGR1 | IFNGR2 | IFNGR1-002 | ENST00000458076 |
| 932c2e20-510c-4aed-879e-b69d90710b64 | Colon.ColoRect-AdenoCA | IFNGR1 | IFNG | IFNGR1-002 | ENST00000458076 |
| 932c2e20-510c-4aed-879e-b69d90710b64 | Colon.ColoRect-AdenoCA | IFNGR1 | SIRPB1 | IFNGR1-002 | ENST00000458076 |
| 932c2e20-510c-4aed-879e-b69d90710b64 | Colon.ColoRect-AdenoCA | IFNGR1 | IFNGR2 | IFNGR1-002 | ENST00000458076 |