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Specific dMDT
Disease-type-specific MDTs
Lost Domain in dMDT
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Gene Name:
Transcript ID:
Transcript Name:
dMDT Interaction Network
Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name
Interaction Lost
Lost Domain (Region)
Lost Domain - Domain Interaction
IGF2R
IGF2R
-M6PR
Man-6-P_recep
(315-479)
Man-6-P_recep
(315-479) -
Man-6-P_recep
Network Density Score:
%
The local network of this protein has more interaction than
% of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
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Sample ID
Disease Type
Gene Name 1
Gene Name 2
Transcript Name
dMDT
357ba9f6-716c-4ef0-8ac8-41977397dbf5
Breast.Breast-AdenoCA
IGF2R
M6PR
IGF2R-005
ENST00000475834
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc
CervixUteri.Cervix-SCC
IGF2R
M6PR
IGF2R-005
ENST00000475834
76733f6c-f1c1-4d57-bf7d-87640d3b88f9
Muscle.Bone-Leiomyo
IGF2R
M6PR
IGF2R-005
ENST00000475834
20c0ac5e-6d20-4730-9efa-67509a7241a3
Ovary.Ovary-AdenoCA
IGF2R
M6PR
IGF2R-005
ENST00000475834
358984cc-b532-4f00-89f4-dda524469b6d
Ovary.Ovary-AdenoCA
IGF2R
M6PR
IGF2R-005
ENST00000475834
912b7bb5-612b-46f3-b8d3-fc43d685ff62
Ovary.Ovary-AdenoCA
IGF2R
M6PR
IGF2R-005
ENST00000475834
f72b280c-e0d0-4b08-bfe3-cd868a2f1b4c
Ovary.Ovary-AdenoCA
IGF2R
M6PR
IGF2R-005
ENST00000475834
Interaction losses with Clinvar proteins
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Gene Name
IGF2R