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Specific dMDT
Disease-type-specific MDTs
Lost Domain in dMDT
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Gene Name:
Transcript ID:
Transcript Name:
dMDT Interaction Network
Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name
Interaction Lost
Lost Domain (Region)
Lost Domain - Domain Interaction
IRAK1
IRAK1
-NFKBIA
Pkinase
(216-516)
Pkinase
(216-516) -
Ank_2
Network Density Score:
%
The local network of this protein has more interaction than
% of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
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Sample ID
Disease Type
Gene Name 1
Gene Name 2
Transcript Name
dMDT
151bb98d-d961-49c1-a54f-8293b3ab2ebd
Colon.ColoRect-AdenoCA
IRAK1
NFKBIA
IRAK1-001
ENST00000369974
310820cc-fc05-45c6-8f04-a44db0828686
Colon.ColoRect-AdenoCA
IRAK1
NFKBIA
IRAK1-001
ENST00000369974
9c1d30c4-c8f0-4ca7-bec7-243f81b7680a
Colon.ColoRect-AdenoCA
IRAK1
NFKBIA
IRAK1-001
ENST00000369974
dd96340b-cc6f-4a3f-b441-c7af1d86684e
Colon.ColoRect-AdenoCA
IRAK1
NFKBIA
IRAK1-001
ENST00000369974
3516aa26-4687-4080-977a-d66ae6486904
Kidney.Kidney-RCC
IRAK1
NFKBIA
IRAK1-001
ENST00000369974
fd0df2dd-fa09-4ec1-8996-c6c6aca9c2a6
Kidney.Kidney-RCC
IRAK1
NFKBIA
IRAK1-001
ENST00000369974
ccdfd8a3-2bc7-474c-b80d-96e8741fe8bc
Stomach.Stomach-AdenoCA
IRAK1
NFKBIA
IRAK1-001
ENST00000369974
a2d46b53-d9bd-4c19-9a0a-fecb48d3c06a
Uterus.Uterus-AdenoCA
IRAK1
NFKBIA
IRAK1-001
ENST00000369974
Interaction losses with Clinvar proteins
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Gene Name
NFKBIA