CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
ITGB5 ITGB5-MYLK Integrin_beta(35-463) Integrin_beta(35-463) - fn3
ITGB5 ITGB5-ITGAV Integrin_beta(35-463) Integrin_beta(35-463) - FG-GAP
ITGB5 ITGB5-ITGA2B Integrin_beta(35-463) Integrin_beta(35-463) - FG-GAP
ITGB5 ITGB5-ITGA1 Integrin_beta(35-463) Integrin_beta(35-463) - FG-GAP
ITGB5 ITGB5-ITGA5 Integrin_beta(35-463) Integrin_beta(35-463) - FG-GAP
ITGB5 ITGB5-ITGA8 Integrin_beta(35-463) Integrin_beta(35-463) - FG-GAP
ITGB5 ITGB5-ITGA7 Integrin_beta(35-463) Integrin_beta(35-463) - FG-GAP
ITGB5 ITGB5-ITGA3 Integrin_beta(35-463) Integrin_beta(35-463) - Integrin_alpha2
ITGB5 ITGB5-ITGA9 Integrin_beta(35-463) Integrin_beta(35-463) - Integrin_alpha2
ITGB5 ITGB5-ITGA6 Integrin_beta(35-463) Integrin_beta(35-463) - Integrin_alpha2
ITGB5 ITGB5-TLN1 Integrin_b_cyt(743-789) Integrin_b_cyt(743-789) - IRS

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA ITGB5 MYLK ITGB5-008 ENST00000481591
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA ITGB5 ITGAV ITGB5-008 ENST00000481591
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA ITGB5 ITGA2B ITGB5-008 ENST00000481591
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA ITGB5 ITGA1 ITGB5-008 ENST00000481591
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA ITGB5 ITGA5 ITGB5-008 ENST00000481591
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA ITGB5 ITGA8 ITGB5-008 ENST00000481591
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA ITGB5 ITGA7 ITGB5-008 ENST00000481591
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA ITGB5 ITGA3 ITGB5-008 ENST00000481591
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA ITGB5 ITGA9 ITGB5-008 ENST00000481591
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA ITGB5 ITGA6 ITGB5-008 ENST00000481591
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA ITGB5 TLN1 ITGB5-008 ENST00000481591
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA ITGB5 MYLK ITGB5-008 ENST00000481591
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA ITGB5 ITGAV ITGB5-008 ENST00000481591
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA ITGB5 ITGA2B ITGB5-008 ENST00000481591
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA ITGB5 ITGA1 ITGB5-008 ENST00000481591
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA ITGB5 ITGA5 ITGB5-008 ENST00000481591
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA ITGB5 ITGA8 ITGB5-008 ENST00000481591
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA ITGB5 ITGA7 ITGB5-008 ENST00000481591
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA ITGB5 ITGA3 ITGB5-008 ENST00000481591
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA ITGB5 ITGA9 ITGB5-008 ENST00000481591
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA ITGB5 ITGA6 ITGB5-008 ENST00000481591
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA ITGB5 TLN1 ITGB5-008 ENST00000481591
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA ITGB5 MYLK ITGB5-008 ENST00000481591
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA ITGB5 ITGAV ITGB5-008 ENST00000481591
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA ITGB5 ITGA2B ITGB5-008 ENST00000481591
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA ITGB5 ITGA1 ITGB5-008 ENST00000481591
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA ITGB5 ITGA5 ITGB5-008 ENST00000481591
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA ITGB5 ITGA8 ITGB5-008 ENST00000481591
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA ITGB5 ITGA7 ITGB5-008 ENST00000481591
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA ITGB5 ITGA3 ITGB5-008 ENST00000481591
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA ITGB5 ITGA9 ITGB5-008 ENST00000481591
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA ITGB5 ITGA6 ITGB5-008 ENST00000481591
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA ITGB5 TLN1 ITGB5-008 ENST00000481591
Interaction losses with Clinvar proteins
Gene Name
ITGA2B
ITGA3
ITGA6
ITGA7
ITGA8
MYLK