dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| MAP3K10 | MAP3K10-MAP2K3 | Pkinase(98-357) | Pkinase(98-357) - Pkinase |
| MAP3K10 | MAP3K10-MAP2K6 | Pkinase(98-357) | Pkinase(98-357) - Pkinase |
| MAP3K10 | MAP3K10-SH3RF1 | Pkinase_Tyr(98-357) | Pkinase_Tyr(98-357) - SH3_9 |
| MAP3K10 | MAP3K10-MAPK8IP2 | Pkinase_Tyr(98-357) | Pkinase_Tyr(98-357) - SH3_9 |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| 15c0fde7-d2b9-434d-81be-196d49244f8d | Ovary.Ovary-AdenoCA | MAP3K10 | MAP2K3 | MAP3K10-004 | ENST00000593502 |
| 15c0fde7-d2b9-434d-81be-196d49244f8d | Ovary.Ovary-AdenoCA | MAP3K10 | MAP2K6 | MAP3K10-004 | ENST00000593502 |
| 15c0fde7-d2b9-434d-81be-196d49244f8d | Ovary.Ovary-AdenoCA | MAP3K10 | SH3RF1 | MAP3K10-004 | ENST00000593502 |
| 15c0fde7-d2b9-434d-81be-196d49244f8d | Ovary.Ovary-AdenoCA | MAP3K10 | MAPK8IP2 | MAP3K10-004 | ENST00000593502 |
Interaction losses with Clinvar proteins
| Gene Name |
|---|