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Specific dMDT
Disease-type-specific MDTs
Lost Domain in dMDT
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Gene Name:
Transcript ID:
Transcript Name:
dMDT Interaction Network
Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name
Interaction Lost
Lost Domain (Region)
Lost Domain - Domain Interaction
NHEJ1
NHEJ1
-XRCC4
XLF
(11-173)
XLF
(11-173) -
XRCC4
Network Density Score:
%
The local network of this protein has more interaction than
% of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
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Sample ID
Disease Type
Gene Name 1
Gene Name 2
Transcript Name
dMDT
SRR19243471
Alzheimer's disease
NHEJ1
XRCC4
NHEJ1-005
ENST00000450447
SRR19243472
Alzheimer's disease
NHEJ1
XRCC4
NHEJ1-005
ENST00000450447
Interaction losses with Clinvar proteins
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Gene Name
NHEJ1
XRCC4