CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
PVRL2 PVRL2-CDH1 V-set(38-152) V-set(38-152) - Cadherin
PVRL2 PVRL2-PVRL4 V-set(38-152) V-set(38-152) - ig
PVRL2 PVRL2-MLLT4 V-set(38-152) V-set(38-152) - PDZ
PVRL2 PVRL2-CRTAM V-set(38-152) V-set(38-152) - V-set
PVRL2 PVRL2-PVRL1 V-set(38-152) V-set(38-152) - V-set
PVRL2 PVRL2-CD226 V-set(38-152) V-set(38-152) - V-set
PVRL2 PVRL2-TIGIT V-set(38-152) V-set(38-152) - V-set
PVRL2 PVRL2-PVRL3 V-set(38-152) V-set(38-152) - V-set

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC PVRL2 CDH1 PVRL2-006 ENST00000585601
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC PVRL2 PVRL4 PVRL2-006 ENST00000585601
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC PVRL2 MLLT4 PVRL2-006 ENST00000585601
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC PVRL2 CRTAM PVRL2-006 ENST00000585601
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC PVRL2 PVRL1 PVRL2-006 ENST00000585601
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC PVRL2 CD226 PVRL2-006 ENST00000585601
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC PVRL2 TIGIT PVRL2-006 ENST00000585601
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC PVRL2 PVRL3 PVRL2-006 ENST00000585601
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
26514a38-7c8b-4afa-9814-e129c58a9120 Ovary.Ovary-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
26514a38-7c8b-4afa-9814-e129c58a9120 Ovary.Ovary-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
26514a38-7c8b-4afa-9814-e129c58a9120 Ovary.Ovary-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
26514a38-7c8b-4afa-9814-e129c58a9120 Ovary.Ovary-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
26514a38-7c8b-4afa-9814-e129c58a9120 Ovary.Ovary-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
26514a38-7c8b-4afa-9814-e129c58a9120 Ovary.Ovary-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
26514a38-7c8b-4afa-9814-e129c58a9120 Ovary.Ovary-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
26514a38-7c8b-4afa-9814-e129c58a9120 Ovary.Ovary-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
358984cc-b532-4f00-89f4-dda524469b6d Ovary.Ovary-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
358984cc-b532-4f00-89f4-dda524469b6d Ovary.Ovary-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
358984cc-b532-4f00-89f4-dda524469b6d Ovary.Ovary-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
358984cc-b532-4f00-89f4-dda524469b6d Ovary.Ovary-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
358984cc-b532-4f00-89f4-dda524469b6d Ovary.Ovary-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
358984cc-b532-4f00-89f4-dda524469b6d Ovary.Ovary-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
358984cc-b532-4f00-89f4-dda524469b6d Ovary.Ovary-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
358984cc-b532-4f00-89f4-dda524469b6d Ovary.Ovary-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
72e75aa6-315d-41dc-a7ea-ff5a20d507a5 Ovary.Ovary-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
72e75aa6-315d-41dc-a7ea-ff5a20d507a5 Ovary.Ovary-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
72e75aa6-315d-41dc-a7ea-ff5a20d507a5 Ovary.Ovary-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
72e75aa6-315d-41dc-a7ea-ff5a20d507a5 Ovary.Ovary-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
72e75aa6-315d-41dc-a7ea-ff5a20d507a5 Ovary.Ovary-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
72e75aa6-315d-41dc-a7ea-ff5a20d507a5 Ovary.Ovary-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
72e75aa6-315d-41dc-a7ea-ff5a20d507a5 Ovary.Ovary-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
72e75aa6-315d-41dc-a7ea-ff5a20d507a5 Ovary.Ovary-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
d6aab8b1-8b8b-443f-b2bc-1539c59efe42 Ovary.Ovary-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
d6aab8b1-8b8b-443f-b2bc-1539c59efe42 Ovary.Ovary-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
d6aab8b1-8b8b-443f-b2bc-1539c59efe42 Ovary.Ovary-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
d6aab8b1-8b8b-443f-b2bc-1539c59efe42 Ovary.Ovary-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
d6aab8b1-8b8b-443f-b2bc-1539c59efe42 Ovary.Ovary-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
d6aab8b1-8b8b-443f-b2bc-1539c59efe42 Ovary.Ovary-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
d6aab8b1-8b8b-443f-b2bc-1539c59efe42 Ovary.Ovary-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
d6aab8b1-8b8b-443f-b2bc-1539c59efe42 Ovary.Ovary-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
f72b280c-e0d0-4b08-bfe3-cd868a2f1b4c Ovary.Ovary-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
f72b280c-e0d0-4b08-bfe3-cd868a2f1b4c Ovary.Ovary-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
f72b280c-e0d0-4b08-bfe3-cd868a2f1b4c Ovary.Ovary-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
f72b280c-e0d0-4b08-bfe3-cd868a2f1b4c Ovary.Ovary-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
f72b280c-e0d0-4b08-bfe3-cd868a2f1b4c Ovary.Ovary-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
f72b280c-e0d0-4b08-bfe3-cd868a2f1b4c Ovary.Ovary-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
f72b280c-e0d0-4b08-bfe3-cd868a2f1b4c Ovary.Ovary-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
f72b280c-e0d0-4b08-bfe3-cd868a2f1b4c Ovary.Ovary-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
1c908135-7fdf-4257-8b9e-92e6aa0850a6 Uterus.Uterus-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
2c5d86e0-2e3d-4259-97e9-023df54c8c56 Uterus.Uterus-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
2c5d86e0-2e3d-4259-97e9-023df54c8c56 Uterus.Uterus-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
2c5d86e0-2e3d-4259-97e9-023df54c8c56 Uterus.Uterus-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
2c5d86e0-2e3d-4259-97e9-023df54c8c56 Uterus.Uterus-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
2c5d86e0-2e3d-4259-97e9-023df54c8c56 Uterus.Uterus-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
2c5d86e0-2e3d-4259-97e9-023df54c8c56 Uterus.Uterus-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
2c5d86e0-2e3d-4259-97e9-023df54c8c56 Uterus.Uterus-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
2c5d86e0-2e3d-4259-97e9-023df54c8c56 Uterus.Uterus-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
4e6ddf28-1fb2-4527-b415-30c714ecde09 Uterus.Uterus-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
4e6ddf28-1fb2-4527-b415-30c714ecde09 Uterus.Uterus-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
4e6ddf28-1fb2-4527-b415-30c714ecde09 Uterus.Uterus-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
4e6ddf28-1fb2-4527-b415-30c714ecde09 Uterus.Uterus-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
4e6ddf28-1fb2-4527-b415-30c714ecde09 Uterus.Uterus-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
4e6ddf28-1fb2-4527-b415-30c714ecde09 Uterus.Uterus-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
4e6ddf28-1fb2-4527-b415-30c714ecde09 Uterus.Uterus-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
4e6ddf28-1fb2-4527-b415-30c714ecde09 Uterus.Uterus-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
b213f9e2-4253-41db-9a05-e91791f4ec7e Uterus.Uterus-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
b213f9e2-4253-41db-9a05-e91791f4ec7e Uterus.Uterus-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
b213f9e2-4253-41db-9a05-e91791f4ec7e Uterus.Uterus-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
b213f9e2-4253-41db-9a05-e91791f4ec7e Uterus.Uterus-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
b213f9e2-4253-41db-9a05-e91791f4ec7e Uterus.Uterus-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
b213f9e2-4253-41db-9a05-e91791f4ec7e Uterus.Uterus-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
b213f9e2-4253-41db-9a05-e91791f4ec7e Uterus.Uterus-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
b213f9e2-4253-41db-9a05-e91791f4ec7e Uterus.Uterus-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
e54b7e44-82a3-4016-bc32-129799097b4c Uterus.Uterus-AdenoCA PVRL2 CDH1 PVRL2-006 ENST00000585601
e54b7e44-82a3-4016-bc32-129799097b4c Uterus.Uterus-AdenoCA PVRL2 PVRL4 PVRL2-006 ENST00000585601
e54b7e44-82a3-4016-bc32-129799097b4c Uterus.Uterus-AdenoCA PVRL2 MLLT4 PVRL2-006 ENST00000585601
e54b7e44-82a3-4016-bc32-129799097b4c Uterus.Uterus-AdenoCA PVRL2 CRTAM PVRL2-006 ENST00000585601
e54b7e44-82a3-4016-bc32-129799097b4c Uterus.Uterus-AdenoCA PVRL2 PVRL1 PVRL2-006 ENST00000585601
e54b7e44-82a3-4016-bc32-129799097b4c Uterus.Uterus-AdenoCA PVRL2 CD226 PVRL2-006 ENST00000585601
e54b7e44-82a3-4016-bc32-129799097b4c Uterus.Uterus-AdenoCA PVRL2 TIGIT PVRL2-006 ENST00000585601
e54b7e44-82a3-4016-bc32-129799097b4c Uterus.Uterus-AdenoCA PVRL2 PVRL3 PVRL2-006 ENST00000585601
Interaction losses with Clinvar proteins
Gene Name
CDH1