CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
SERPING1 SERPING1-SERPINE1 Serpin(145-498) Serpin(145-498) - Serpin
SERPING1 SERPING1-SERPINF2 Serpin(145-498) Serpin(145-498) - Serpin
SERPING1 SERPING1-SERPINA1 Serpin(145-498) Serpin(145-498) - Serpin
SERPING1 SERPING1-F12 Serpin(145-498) Serpin(145-498) - Trypsin
SERPING1 SERPING1-KLKB1 Serpin(145-498) Serpin(145-498) - Trypsin
SERPING1 SERPING1-MASP1 Serpin(145-498) Serpin(145-498) - Trypsin
SERPING1 SERPING1-PLG Serpin(145-498) Serpin(145-498) - Trypsin
SERPING1 SERPING1-KLK4 Serpin(145-498) Serpin(145-498) - Trypsin
SERPING1 SERPING1-C1S Serpin(145-498) Serpin(145-498) - Trypsin
SERPING1 SERPING1-CFD Serpin(145-498) Serpin(145-498) - Trypsin
SERPING1 SERPING1-MASP2 Serpin(145-498) Serpin(145-498) - Trypsin
SERPING1 SERPING1-EGF Serpin(145-498) Serpin(145-498) - FXa_inhibition
SERPING1 SERPING1-GAS6 Serpin(145-498) Serpin(145-498) - FXa_inhibition
SERPING1 SERPING1-PROS1 Serpin(145-498) Serpin(145-498) - FXa_inhibition

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 SERPINE1 SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 SERPINF2 SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 SERPINA1 SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 F12 SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 KLKB1 SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 MASP1 SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 PLG SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 KLK4 SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 C1S SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 CFD SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 MASP2 SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 EGF SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 GAS6 SERPING1-006 ENST00000340687
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA SERPING1 PROS1 SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 SERPINE1 SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 SERPINF2 SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 SERPINA1 SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 F12 SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 KLKB1 SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 MASP1 SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 PLG SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 KLK4 SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 C1S SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 CFD SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 MASP2 SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 EGF SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 GAS6 SERPING1-006 ENST00000340687
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA SERPING1 PROS1 SERPING1-006 ENST00000340687
Interaction losses with Clinvar proteins
Gene Name
C1S
CFD
EGF
F12
KLK4
KLKB1
MASP1
MASP2
PLG
PROS1
SERPINA1
SERPINE1
SERPINF2
SERPING1