dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| SHC3 | SHC3-SHC2 | SH2(499-570) | SH2(499-570) - SH2 |
| SHC3 | SHC3-GRB2 | SH2(499-570) | SH2(499-570) - SH2 |
| SHC3 | SHC3-SRC | SH2(499-570) | SH2(499-570) - SH2 |
| SHC3 | SHC3-SHC1 | SH2(499-570) | SH2(499-570) - SH2 |
| SHC3 | SHC3-IGF1R | SH2(499-570) | SH2(499-570) - fn3 |
| SHC3 | SHC3-INSR | SH2(499-570) | SH2(499-570) - fn3 |
| SHC3 | SHC3-FLT4 | SH2(499-570) | SH2(499-570) - Pkinase_Tyr |
| SHC3 | SHC3-ERBB3 | SH2(499-570) | SH2(499-570) - Pkinase_Tyr |
| SHC3 | SHC3-ERBB2 | SH2(499-570) | SH2(499-570) - Pkinase_Tyr |
| SHC3 | SHC3-EGFR | SH2(499-570) | SH2(499-570) - Pkinase_Tyr |
| SHC3 | SHC3-NTRK2 | SH2(499-570) | SH2(499-570) - Pkinase_Tyr |
| SHC3 | SHC3-ERBB4 | SH2(499-570) | SH2(499-570) - Pkinase_Tyr |
| SHC3 | SHC3-NTRK1 | SH2(499-570) | SH2(499-570) - Pkinase_Tyr |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch