dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| SOCS2 | SOCS2-STAT3 | SH2(48-129) | SH2(48-129) - SH2 |
| SOCS2 | SOCS2-STAT5B | SH2(48-129) | SH2(48-129) - SH2 |
| SOCS2 | SOCS2-SOCS1 | SH2(48-129) | SH2(48-129) - SH2 |
| SOCS2 | SOCS2-SOCS3 | SH2(48-129) | SH2(48-129) - SH2 |
| SOCS2 | SOCS2-LCK | SH2(48-129) | SH2(48-129) - SH2 |
| SOCS2 | SOCS2-STAT5A | SH2(48-129) | SH2(48-129) - SH2 |
| SOCS2 | SOCS2-STAT1 | SH2(48-129) | SH2(48-129) - SH2 |
| SOCS2 | SOCS2-JAK2 | SH2(48-129) | SH2(48-129) - SH2 |
| SOCS2 | SOCS2-CISH | SH2(48-129) | SH2(48-129) - SH2 |
| SOCS2 | SOCS2-EPOR | SH2(48-129) | SH2(48-129) - fn3 |
| SOCS2 | SOCS2-GHR | SH2(48-129) | SH2(48-129) - fn3 |
| SOCS2 | SOCS2-IGF1R | SH2(48-129) | SH2(48-129) - fn3 |
| SOCS2 | SOCS2-INSR | SH2(48-129) | SH2(48-129) - fn3 |
| SOCS2 | SOCS2-TYK2 | SH2(48-129) | SH2(48-129) - Pkinase_Tyr |
| SOCS2 | SOCS2-JAK1 | SH2(48-129) | SH2(48-129) - Pkinase_Tyr |
| SOCS2 | SOCS2-CUL5 | SOCS_box(161-195) | SOCS_box(161-195) - Cullin |
| SOCS2 | SOCS2-TCEB1 | SOCS_box(161-195) | SOCS_box(161-195) - Skp1_POZ |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch