dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| SRGAP1 | SRGAP1-ARHGEF6 | FCH(23-119) | FCH(23-119) - SH3_9 |
| SRGAP1 | SRGAP1-ARHGEF4 | FCH(23-119) | FCH(23-119) - SH3_9 |
| SRGAP1 | SRGAP1-ARHGEF16 | FCH(23-119) | FCH(23-119) - SH3_9 |
| SRGAP1 | SRGAP1-ITSN1 | FCH(23-119) | FCH(23-119) - SH3_9 |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| 6278b5a4-b93b-4926-8158-dc7fc871c1cc | Muscle.Bone-Leiomyo | SRGAP1 | ARHGEF6 | SRGAP1-003 | ENST00000543397 |
| 6278b5a4-b93b-4926-8158-dc7fc871c1cc | Muscle.Bone-Leiomyo | SRGAP1 | ARHGEF4 | SRGAP1-003 | ENST00000543397 |
| 6278b5a4-b93b-4926-8158-dc7fc871c1cc | Muscle.Bone-Leiomyo | SRGAP1 | ARHGEF16 | SRGAP1-003 | ENST00000543397 |
| 6278b5a4-b93b-4926-8158-dc7fc871c1cc | Muscle.Bone-Leiomyo | SRGAP1 | ITSN1 | SRGAP1-003 | ENST00000543397 |
Interaction losses with Clinvar proteins
| Gene Name |
|---|
| SRGAP1 |