CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
CASP1 14 13 CASP1-BCL2L1 CARD(4-89)-Bcl-2 CASP1-009 ENST00000526568
CASP1 14 13 CASP1-NFKB1 CARD(4-89)-Death CASP1-009 ENST00000526568
CASP1 14 13 CASP1-NFKB2 CARD(4-89)-Death CASP1-009 ENST00000526568
CASP1 14 13 CASP1-MYD88 CARD(4-89)-Death CASP1-009 ENST00000526568
CASP1 14 13 CASP1-NOD1 CARD(4-89)-CARD CASP1-009 ENST00000526568
CASP1 14 13 CASP1-PYCARD CARD(4-89)-CARD CASP1-009 ENST00000526568
CASP1 14 13 CASP1-NOD2 CARD(4-89)-CARD CASP1-009 ENST00000526568
CASP1 14 13 CASP1-NLRC4 CARD(4-89)-CARD CASP1-009 ENST00000526568
CASP1 14 13 CASP1-CARD8 CARD(4-89)-CARD CASP1-009 ENST00000526568
CASP1 14 13 CASP1-CASP5 CARD(4-89)-CARD CASP1-009 ENST00000526568
CASP1 14 13 CASP1-CASP4 CARD(4-89)-CARD CASP1-009 ENST00000526568
CASP1 14 13 CASP1-APAF1 CARD(4-89)-CARD CASP1-009 ENST00000526568
CASP1 14 13 CASP1-NLRP1 CARD(4-89)-CARD CASP1-009 ENST00000526568

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 BCL2L1 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 NFKB1 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 NFKB2 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 MYD88 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 NOD1 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 PYCARD CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 NOD2 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 NLRC4 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 CARD8 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 CASP5 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 CASP4 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 APAF1 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Blood.Lymph-BNHL CASP1 NLRP1 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 BCL2L1 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 NFKB1 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 NFKB2 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 MYD88 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 NOD1 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 PYCARD CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 NOD2 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 NLRC4 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 CARD8 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 CASP5 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 CASP4 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 APAF1 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL CASP1 NLRP1 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 BCL2L1 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 NFKB1 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 NFKB2 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 MYD88 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 NOD1 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 PYCARD CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 NOD2 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 NLRC4 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 CARD8 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 CASP5 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 CASP4 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 APAF1 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Blood.Lymph-BNHL CASP1 NLRP1 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 BCL2L1 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 NFKB1 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 NFKB2 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 MYD88 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 NOD1 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 PYCARD CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 NOD2 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 NLRC4 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 CARD8 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 CASP5 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 CASP4 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 APAF1 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver.Liver-HCC CASP1 NLRP1 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 BCL2L1 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 NFKB1 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 NFKB2 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 MYD88 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 NOD1 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 PYCARD CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 NOD2 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 NLRC4 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 CARD8 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 CASP5 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 CASP4 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 APAF1 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus.Uterus-AdenoCA CASP1 NLRP1 CASP1-009 ENST00000526568