CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction lost due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain<-->Domain Interaction
CASP1 CASP1-BCL2L1 CARD(4-89) CARD(4-89)--Bcl-2
CASP1 CASP1-NFKB1 CARD(4-89) CARD(4-89)--Death
CASP1 CASP1-NFKB2 CARD(4-89) CARD(4-89)--Death
CASP1 CASP1-MYD88 CARD(4-89) CARD(4-89)--Death
CASP1 CASP1-NOD1 CARD(4-89) CARD(4-89)--CARD
CASP1 CASP1-PYCARD CARD(4-89) CARD(4-89)--CARD
CASP1 CASP1-NOD2 CARD(4-89) CARD(4-89)--CARD
CASP1 CASP1-NLRC4 CARD(4-89) CARD(4-89)--CARD
CASP1 CASP1-CARD8 CARD(4-89) CARD(4-89)--CARD
CASP1 CASP1-CASP5 CARD(4-89) CARD(4-89)--CARD
CASP1 CASP1-CASP4 CARD(4-89) CARD(4-89)--CARD
CASP1 CASP1-APAF1 CARD(4-89) CARD(4-89)--CARD
CASP1 CASP1-NLRP1 CARD(4-89) CARD(4-89)--CARD

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Protein Interaction Lost due to the MDT switch in all disease types
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 BCL2L1 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 NFKB1 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 NFKB2 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 MYD88 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 NOD1 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 PYCARD CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 NOD2 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 NLRC4 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 CARD8 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 CASP5 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 CASP4 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 APAF1 CASP1-009 ENST00000526568
953e90e7-a9a6-47d6-bd4a-fe18e780b9e0 Lymph-BNHL CASP1 NLRP1 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 BCL2L1 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 NFKB1 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 NFKB2 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 MYD88 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 NOD1 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 PYCARD CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 NOD2 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 NLRC4 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 CARD8 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 CASP5 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 CASP4 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 APAF1 CASP1-009 ENST00000526568
a0091162-1691-4b4c-990f-c58369e09548 Lymph-BNHL CASP1 NLRP1 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 BCL2L1 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 NFKB1 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 NFKB2 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 MYD88 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 NOD1 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 PYCARD CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 NOD2 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 NLRC4 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 CARD8 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 CASP5 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 CASP4 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 APAF1 CASP1-009 ENST00000526568
f43a92ce-fc88-4e40-be91-0b5641ad844e Lymph-BNHL CASP1 NLRP1 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 BCL2L1 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 NFKB1 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 NFKB2 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 MYD88 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 NOD1 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 PYCARD CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 NOD2 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 NLRC4 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 CARD8 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 CASP5 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 CASP4 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 APAF1 CASP1-009 ENST00000526568
e5e12896-2cf3-4d5d-8f79-00cd964fc132 Liver-HCC CASP1 NLRP1 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 BCL2L1 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 NFKB1 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 NFKB2 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 MYD88 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 NOD1 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 PYCARD CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 NOD2 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 NLRC4 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 CARD8 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 CASP5 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 CASP4 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 APAF1 CASP1-009 ENST00000526568
a1d4b9ef-6fe5-49b5-9bb5-686d253baa4c Uterus-AdenoCA CASP1 NLRP1 CASP1-009 ENST00000526568
Protein Interaction Lost with Proteins annotated in Clinvar
Gene Name
CARD8
MYD88
NFKB1
NFKB2
NLRC4
NLRP1
NOD2