CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
PRKCA 58 47 PRKCA-ACTB Pkinase(340-583)-Actin PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-NFKB1 Pkinase(340-583)-Ank PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-ITGB4 Pkinase(340-583)-fn3 PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-MAPK1 Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-RPS6KB1 Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-RAF1 Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-MAPK3 Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-PRKCG Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-BRAF Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-PRKCB Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-PRKCE Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-ADRBK1 Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-PRKCD Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-PDPK1 Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-CHUK Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-CDK1 Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-CHEK1 Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-RPS6KA2 Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-IKBKB Pkinase(340-583)-Pkinase PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-HRAS Pkinase(340-583)-Ras PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-RAC1 Pkinase(340-583)-Ras PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-RAB4A Pkinase(340-583)-Ras PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-RHOA Pkinase(340-583)-Ras PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-ELAVL1 Pkinase(340-583)-RRM_1 PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-CCNB1 Pkinase(340-583)-Cyclin_N PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-PLD1 Pkinase(340-583)-PH PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-TEC Pkinase(340-583)-PH PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-GRB10 Pkinase(340-583)-PH PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-SOS1 Pkinase(340-583)-PH PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-GRB7 Pkinase(340-583)-PH PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-UBC Pkinase(340-583)-ubiquitin PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-VCAM1 Pkinase(340-583)-I-set PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-NRG2 Pkinase(340-583)-I-set PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-EGFR Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-FER Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-KIT Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-YES1 Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-FES Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-PTK2B Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-LCK Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-ERBB4 Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-FYN Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-RET Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-SRC Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-JAK2 Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-LYN Pkinase(340-583)-Pkinase_Tyr PRKCA-001 ENST00000578063
PRKCA 58 47 PRKCA-NFKBIA Pkinase(340-583)-Ank_2 PRKCA-001 ENST00000578063

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA ACTB PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA NFKB1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA ITGB4 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA MAPK1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA RPS6KB1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA RAF1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA MAPK3 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA PRKCG PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA BRAF PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA PRKCB PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA PRKCE PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA ADRBK1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA PRKCD PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA PDPK1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA CHUK PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA CDK1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA CHEK1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA RPS6KA2 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA IKBKB PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA HRAS PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA RAC1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA RAB4A PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA RHOA PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA ELAVL1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA CCNB1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA PLD1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA TEC PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA GRB10 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA SOS1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA GRB7 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA UBC PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA VCAM1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA NRG2 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA EGFR PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA FER PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA KIT PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA YES1 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA FES PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA PTK2B PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA LCK PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA ERBB4 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA FYN PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA RET PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA SRC PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA JAK2 PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA LYN PRKCA-001 ENST00000578063
b5e61a38-2067-473e-8eb3-0d8c259b7e67 Lung.Lung-SCC PRKCA NFKBIA PRKCA-001 ENST00000578063