CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name
# of
Interaction*
# of Missed
Interaction
Interaction
Lost
Domain Int
Lost
Transcript Name dMDT
TOP2A 5 5 TOP2A-TOP2B DNA_gyraseB(266-426)-DNA_gyraseB TOP2A-006 ENST00000577541
TOP2A 5 5 TOP2A-WRN Toprim(456-567)-DEAD TOP2A-006 ENST00000577541
TOP2A 5 5 TOP2A-RECQL5 Toprim(456-567)-DEAD TOP2A-006 ENST00000577541
TOP2A 5 5 TOP2A-BLM Toprim(456-567)-DEAD TOP2A-006 ENST00000577541
TOP2A 5 5 TOP2A-RECQL Toprim(456-567)-DEAD TOP2A-006 ENST00000577541

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch